MOUNTAIN
RESEARCH
CENTER

Polytechnic Institute
of Bragança

image01

CIMO

CIMO - Mountain Research Center. See video HERE

FROM NATURE TO PRODUCTS, TOWARDS SUSTAINABILITY.

Sandrina Alves Heleno

Junior Researcher
Group: Sustainable Processes and Products
Phone: 273303285
E-mail: sheleno@ipb.pt
ORCID: 000-0001-7224-1098
Scopus Author ID: 30067731800

Career

  • Since 2019: Junior Researcher (national funding by FCT, Foundation dor Science and Tecnhology) at CIMO-IPB, Portugal
  • 2015 - 2019: Pos-Doc researcher (SFRH/BPD/101413/2014)
  • 2015 - 2015: Pos-Doc researcher in the project ( NORTE-07-0124-FEDER- 0000014) - Polymer Reaction Engineering, Laboratory of Separation and Reaction Engineering

Qualifications

  • 2014 - PhD. in Sciences, specialty in chemistry, University of Minho Minho, Braga, Portugal
  • 2010 - MSc. in Biotechnology, Polytechnic Institute of Bragança, Portugal
  • 2008 - First degree in Biotechnological engineering, Polytechnic Institute of Bragança, Portugal

Awards and Honors

  • 2022 - Promove Program (2020-2021) - Initiative B - Ideas with the potential to become innovative pilot projects
  • 2017 - Ward for the best oral communication in the VIII Fórum Ibérico de Úlceras e Feridas, Guimarães, Portugal

Interests

  • Extraction, purification and characterization of bioactive compounds such as mycosterols present in mushrooms
  • Bioactivity extracts and isolated compounds from mushrooms
  • Synthesis of mycosterol derivatives: chemical characterization, bioactivity and stability
  • Development of novel functional foods through the incorporation of extracts and bioactive compounds
  • Stabilization of extracts and isolated compounds in foodstuff
  • Development of cosmeceutical formulations through the incorporation of extracts and bioactive compounds
  • Stabilization studies of extracts and compounds in cosmeceutical formulations

Projects:

TextBlueStyle - Obtenção de corantes azuis naturais e sustentáveis para aplicação têxtil
Funding body: Fundação LA CAIXA - Promove - Projetos Piloto 2023
Reference:
Principal Investigator:Manuel Ricardo Costa Calhelha
Start: 2023-07-01
End: 2026-06-30
BEONNAT - Innovative value chains from tree & shrub species grown in marginal lands as a source of biomass for bio-based industries
Funding body: Horizon 2020
Reference: BBI-2019-SO1-R1 - 887917 – BEONNAT
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-07-01
End: 2025-06-30
Aquavitae - Thermal water as a source of life and health
Funding body: PROMOVE 2020
Reference: PD20-00003
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-09-01
End: 2024-05-31
LOCALNUTLEG - Developing of innovative plant- based added-value food products through the promotion of LOCAL Mediterranean NUT and LEGume crops
Funding body: PRIMA - TOPIC: 1.3.1-2020 (IA) Valorising the health benefits of the Traditional Mediterranean food products
Reference:
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-01-01
End: 2024-01-01
WASTESILK - Silk Sericin as an industrial wastewater with valuable biomedical potential
Funding body: FCT
Reference:
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-01-01
End: 2024-01-01
PulpIng - Development of Pumpking Pulp Formulations using a Sustainable Integrated Strategy Participant No PI name Organisation
Funding body: FCT/PRIMA
Reference: PRIMA/0007/2019
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-09-01
End: 2023-08-31
CôaMedPlants - Preservação do património natural e cultural e validação científica das práticas com plantas medicinais do Vale do Côa
Funding body: FCT, within the scope of Vale do Côa International Research Awards
Reference: COA/BRB/0019/2019
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-07-01
End: 2023-06-30
PreVineGrape - Desenvolvimento de um biofungicida para combate a doenças da videira
Funding body: POCI-FEDER
Reference:
Principal Investigator:Sandrina Alves Heleno
Start: 2021-01-01
End: 2023-06-29
Bio4drinks - Obtenção de Ingredientes Naturais Multifuncionais para a Indústria de Bebidas
Funding body: Programas I&DT Copromoção do Portugal 2020 — Territórios do Interior
Reference:
Principal Investigator:Sandrina Alves Heleno
Start: 2021-09-01
End: 2023-05-30
VALORNATURAL - Valorização de Recursos Naturais através da Extração de Ingredientes de Elevado Valor Acrescentado para Aplicações na Indústria Alimentar
Funding body: PORTUGAL 2020- SI-IDT - Programas mobilizadores
Reference:
Principal Investigator:Lillian Bouçada de Barros
Start: 2018-09-01
End: 2022-08-31
PlantCovid - Aplicações de extratos de plantas com ação dirigida ao SARS-CoV-2
Funding body: I&D Empresas - COVID19
Reference: NORTE-01-02B/-FEDER-054870
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-07-14
End: 2021-07-13
Halófitas Vermelhas - Halófitas vermelhas como nova fonte de biomoléculas com aplicação na indústria alimentar, nutracêutica e medicina
Funding body: Programa bilateral Portugal/Tunísia
Reference:
Principal Investigator:João Carlos Martins Barreira
Start: 2019-01-01
End: 2020-01-01
DeCodE - Bring natural colorants and preservers into a real alternative to artificial additives through a strategy of open data and experience based research
Funding body: FCT-SAICT
Reference:
Principal Investigator:Isabel Cristina Fernandes Rodrigues Ferreira
Start: 2017-10-01
End: 2019-10-30

Total results: 102
1
de Oliveira I.,Chrysargyris A.,Finimundy T.C.,Carocho M.,Santos-Buelga C.,Calhelha R.C.,Tzortzakis N.,Barros L.,Heleno S.A.
Magnesium and manganese induced changes on chemical, nutritional, antioxidant and antimicrobial properties of the pansy and Viola edible flowers
Food Chemistry, 438, , 2024

2
Chtioui W.,Heleno S.,Migheli Q.,Rodrigues P.
Plant extracts as biocontrol agents against Aspergillus carbonarius growth and ochratoxin A production in grapes
International Journal of Food Microbiology, 407, , 2023

3
Ueda J.M.,Griebler K.R.,Finimundy T.C.,Rodrigues D.B.,Veríssimo L.,Pires T.C.S.P.,Gonçalves J.,Fernandes I.P.,Pereira E.,Barros L.,Heleno S.A.,Calhelha R.C.
Polyphenol Composition by HPLC-DAD-(ESI-)MS/MS and Bioactivities of Extracts from Grape Agri-Food Wastes
Molecules, 28, , 2023

4
Plasencia P.,Heleno S.A.,Finimundy T.,Carocho M.,Calhelha R.C.,Añibarro-Ortega M.,Alves M.J.,Oludemi T.,Quidiongo N.,Barreiro F.,García P.A.,Ferreira I.C.F.R.,Barros L.
Recovery of High Valuable Bioactive Molecules from Vaccinium myrtillus L. Bioresidues
Waste and Biomass Valorization, 14, 2873-2884, 2023

5
Roriz C.L.,Carocho M.,Alves M.J.,Rodrigues P.,Morales P.,Ferreira I.C.F.R.,Heleno S.A.,Barros L.
Betacyanins obtained from alternative novel sources as natural food colorant additives: incorporated in savory and sweet food products
Food and Function, 14, 8775-8784, 2023

6
Martins de Deus B.,Fernandes C.,Molina A.K.,Xavier V.,Pires T.C.S.P.,Mandim F.,Heleno S.A.,Finimundy T.C.,Barros L.
Chemical Characterization, Bioactivity and Toxicity of European Flora Plant Extracts in Search for Potential Natural Origin Preservatives
Plants, 12, , 2023

7
de Oliveira I.,Chrysargyris A.,Heleno S.A.,Carocho M.,Calhelha R.C.,Dias M.I.,Petrović J.,Soković M.,Petropoulos S.A.,Santos-Buelga C.,Tzortzakis N.,Barros L.
Effects of the extraction techniques on the chemical composition and bioactive properties of lemon balm (Melissa officinalis L.) plants grown under different cropping and irrigation regimes
Food Research International, 170, , 2023

8
Rodrigues D.B.,Veríssimo L.,Finimundy T.,Rodrigues J.,Oliveira I.,Gonçalves J.,Fernandes I.P.,Barros L.,Heleno S.A.,Calhelha R.C.
Chemical and Bioactive Screening of Green Polyphenol-Rich Extracts from Chestnut By-Products: An Approach to Guide the Sustainable Production of High-Added Value Ingredients
Foods, 12, , 2023

9
Inumaro R.S.,Casalvara R.F.A.,Corrêa R.C.G.,Barros L.,Pereira C.,Calhelha R.M.,Heleno S.A.,Pimentel T.C.,Gonçalves J.E.,Cardozo-Filho L.
Supercritical fluid-assisted extraction of hop cone residue from craft breweries
Journal of CO2 Utilization, 72, , 2023

10
Castillo A.,Finimundy T.C.,Heleno S.A.,Rodrigues P.,Fernandes F.A.,Pereira S.,Lores M.,Barros L.,Garcia-Jares C.
The generally recognized as safe (GRAS) microalgae Haematococcus pluvialis (wet) as a multifunctional additive for coloring and improving the organoleptic and functional properties of foods
Food and Function, 14, 6023-6035, 2023

11
Mediavilla I.,Bados R.,Barros L.,Xavier V.,Finimundy T.C.,Pires T.C.S.P.,Heleno S.A.,Calhelha R.C.,Amaral J.S.,Rizzo A.M.,Casini D.,Lombardi G.,Chiaramonti D.,Cámara M.,Suárez A.,Ardid T.,Esteban L.S.
Assessment of the Use of Common Juniper (Juniperus communis L.) Foliage following the Cascade Principle
Molecules, 28, , 2023

12
Shiraishi C.S.H.,Zbiss Y.,Roriz C.L.,Dias M.I.,Prieto M.A.,Calhelha R.C.,Alves M.J.,Heleno S.A.,da Cunha Mendes V.,Carocho M.,Abreu R.M.V.,Barros L.
Fig Leaves (Ficus carica L.): Source of Bioactive Ingredients for Industrial Valorization
Processes, 11, , 2023

13
14
Carocho M.,Heleno S.A.,Barros L.
Natural Secondary Metabolites: From Nature, Through Science, to Industry
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 1-965, 2023

15
Hached H.,Cassani L.,Zbiss Y.,Fraga-Corral M.,Oliveira I.,Pereira A.G.,Prieto M.A.,Heleno S.A.,Carocho M.
Non-alkaloid nitrogen-containing compounds from fungi
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 627-646, 2023

16
Liberal Â.,Cardoso R.V.C.,Heleno S.A.,Fernandes Â.,Barros L.,Martins A.
Phenolic Acids from Fungi
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 475-495, 2023

17
de Oliveira I.,Albuquerque B.,Ueda J.M.,Alves M.J.,Ferreira I.C.F.R.,Barros L.,Heleno S.A.
New challenges and opportunities from secondary metabolites
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 925-965, 2023

18
Carocho M.,Heleno S.A.,Barros L.
Preface
Natural Secondary Metabolites: From Nature, Through Science, to Industry, v, 2023

19
Xavier V.,Spréa R.,Finimundy T.C.,Heleno S.A.,Amaral J.S.,Barros L.,Ferreira I.C.F.R.
Terpenes
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 107-156, 2023

20
Calhelha R.C.,Haddad H.,Ribeiro L.,Heleno S.A.,Carocho M.,Barros L.
Inflammation: What’s There and What’s New?
Applied Sciences (Switzerland), 13, , 2023

21
Heleno S.A.,Carocho M.,Reis F.S.,Pires T.C.S.P.,Pintado M.,Ferreira I.C.F.R.,Barros L.
Plant Extracts and SARS-CoV-2: Research and Applications
Life, 13, , 2023

22
Albuquerque B.R.,Pinela J.,Pereira C.,Mandim F.,Heleno S.,Oliveira M.B.P.P.,Barros L.
Recovery of anthocyanins from Eugenia spp. fruit peels: a comparison between heat- and ultrasound-assisted extraction
Sustainable Food Technology, , 2023

23
Albuquerque B.R.,Pinela J.,Pereira C.,Calhelha R.C.,Oliveira I.,Heleno S.,Oliveira M.B.P.P.,Barros L.
Optimization and comparison of heat- and ultrasound-assisted extraction methods for anthocyanin recovery from Sicana odorifera fruit epicarp
Biomass Conversion and Biorefinery, , 2023

24
Barros L.,Heleno S.A.,Prieto M.A.
Natural Products as Health Promoters
Current Pharmaceutical Design, 29, 803, 2023

25
Ueda J.M.,Milho C.,Heleno S.A.,Soria-Lopez A.,Carpena M.,Alves M.J.,Pires T.,Prieto M.A.,Simal-Gandara J.,Calhelha R.C.,Ferreira I.C.F.R.,Barros L.
Emerging Strategies to Combat Methicillin-resistant Staphylococcus aureus (MRSA): Natural Agents with High Potential
Current Pharmaceutical Design, 29, 837-851, 2023

26
Zaier M.M.,Heleno S.A.,Mandim F.,Calhelha R.C.,Ferreira I.C.F.R.,Achour L.,Kacem A.,Dias M.I.,Barros L.
Effects of the seasonal variation in the phytochemical composition and bioactivities of the wild halophyte Suaeda fruticosa
Food Bioscience, 50, , 2022

27
Durazzo A.,Carocho M.,Heleno S.A.,Pedrosa M.C.,Ueda J.M.,Barros L.,Souto E.B.,Santini A.,Lucarini M.
Fermented food/beverage and health: current perspectives
Rendiconti Lincei, 33, 729-738, 2022

28
de la Fuente B.,Pinela J.,Calhelha R.C.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Sea bass (Dicentrarchus labrax) and sea bream (Sparus aurata) head oils recovered by microwave-assisted extraction: Nutritional quality and biological properties
Food and Bioproducts Processing, 136, 97-105, 2022

29
Polyzos N.,Paschoalinotto B.H.,Compocholi M.,Pinela J.,Heleno S.A.,Calhelha R.C.,Dias M.I.,Barros L.,Petropoulos S.A.
Fertilization of Pot-Grown Cichorium spinosum L.: How It Can Affect Plant Growth, Chemical Profile, and Bioactivities of Edible Parts?
Horticulturae, 8, , 2022

30
Durazzo A.,Carocho M.,Heleno S.,Barros L.,Souto E.B.,Santini A.,Lucarini M.
Food dyes and health: Literature quantitative research analysis
Measurement: Food, 7, , 2022

31
Alonso-Esteban J.I.,Carocho M.,Barros D.,Velho M.V.,Heleno S.,Barros L.
Chemical composition and industrial applications of Maritime pine (Pinus pinaster Ait.) bark and other non-wood parts
Reviews in Environmental Science and Biotechnology, 21, 583-633, 2022

32
de la Fuente B.,Pinela J.,Mandim F.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Nutritional and bioactive oils from salmon (Salmo salar) side streams obtained by Soxhlet and optimized microwave-assisted extraction
Food Chemistry, 386, , 2022

33
Fernandes F.A.,Pedrosa M.C.,Ueda J.M.,Ferreira E.,Rodrigues P.,Heleno S.A.,Carocho M.,Prieto M.A.,Ferreira I.C.F.R.,Barros L.
Improving the physicochemical properties of a traditional Portuguese cake - “económicos” with chestnut flour
Food and Function, 13, 8243-8253, 2022

34
Fernandes F.A.,Heleno S.A.,Pinela J.,Carocho M.,Prieto M.A.,Ferreira I.C.F.R.,Barros L.
Recovery of Citric Acid from Citrus Peels: Ultrasound-Assisted Extraction Optimized by Response Surface Methodology
Chemosensors, 10, , 2022

35
Ueda J.M.,Pedrosa M.C.,Heleno S.A.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Food Additives from Fruit and Vegetable By-Products and Bio-Residues: A Comprehensive Review Focused on Sustainability
Sustainability (Switzerland), 14, , 2022

36
Derbassi N.B.,Pedrosa M.C.,Heleno S.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Plant volatiles: Using Scented molecules as food additives
Trends in Food Science and Technology, 122, 97-103, 2022

37
Roriz C.L.,Heleno S.A.,Alves M.J.,Oliveira M.B.P.P.,Pinela J.,Dias M.I.,Calhelha R.C.,Morales P.,Ferreira I.C.F.R.,Barros L.
Red pitaya (Hylocereus costaricensis) peel as a source of valuable molecules: Extraction optimization to recover natural colouring agents
Food Chemistry, 372, , 2022

38
Derbassi N.,C. Pedrosa M.,Heleno S.,Fernandes F.,Dias M.I.,Calhelha R.C.,Rodrigues P.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Arbutus unedo leaf extracts as potential dairy preservatives: case study on quark cheese
Food and Function, , 2022

39
Xavier V.,Finimundy T.C.,Heleno S.A.,Amaral J.S.,Calhelha R.C.,Vaz J.,Pires T.C.S.P.,Mediavilla I.,Esteban L.S.,Ferreira I.C.F.R.,Barros L.
Chemical and bioactive characterization of the essential oils obtained from three mediterranean plants
Molecules, 26, , 2021

40
Pedrosa M.C.,Lima L.,Heleno S.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Food metabolites as tools for authentication, processing, and nutritive value assessment
Foods, 10, , 2021

41
Vega E.N.,Molina A.K.,Pereira C.,Dias M.I.,Heleno S.A.,Rodrigues P.,Fernandes I.P.,Barreiro M.F.,Stojković D.,Soković M.,Carocho M.,Barreira J.C.M.,Ferreira I.C.F.R.,Barros L.
Anthocyanins from rubus fruticosus l. And morus nigra l. applied as food colorants: A natural alternative
Plants, 10, , 2021

42
Ceccanti C.,Finimundy T.C.,Heleno S.A.,Pires T.C.S.P.,Calhelha R.C.,Guidi L.,Ferreira I.C.F.R.,Barros L.
Differences in the phenolic composition and nutraceutical properties of freeze dried and oven-dried wild and domesticated samples of Sanguisorba minor Scop
LWT, 145, , 2021

43
Roriz C.L.,Xavier V.,Heleno S.A.,Pinela J.,Dias M.I.,Calhelha R.C.,Morales P.,Ferreira I.C.F.R.,Barros L.
Chemical and bioactive features of amaranthus caudatus l. Flowers and optimized ultrasound-assisted extraction of betalains
Foods, 10, , 2021

44
Ueda J.M.,Pedrosa M.C.,Fernandes F.A.,Rodrigues P.,Melgar B.,Dias M.I.,Pinela J.,Calhelha R.C.,Ivanov M.,Soković M.,Heleno S.A.,Carocho M.,Ineu R.P.,Ferreira I.C.F.R.,Barros L.
Promising preserving agents from sage and basil: A case study with yogurts
Foods, 10, , 2021

45
Gómez-Mejía E.,Roriz C.L.,Heleno S.A.,Calhelha R.,Dias M.I.,Pinela J.,Rosales-Conrado N.,León-González M.E.,Ferreira I.C.F.R.,Barros L.
Valorisation of black mulberry and grape seeds: Chemical characterization and bioactive potential
Food Chemistry, 337, , 2021

46
Albuquerque B.R.,Heleno S.A.8.,Oliveira M.B.P.P.,Barros L.,Ferreira I.C.F.R.
Phenolic compounds: Current industrial applications, limitations and future challenges
Food and Function, 12, 14-29, 2021

47
Pedrosa M.C.,Ueda J.M.,Melgar B.,Dias M.I.,Pinela J.,Calhelha R.C.,Ivanov M.,Soković M.,Heleno S.,da Silva A.B.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Preservation of chocolate muffins with Lemon Balm, Oregano, and Rosemary extracts
Foods, 10, , 2021

48
Roriz C.L.,Heleno S.A.,Carocho M.,Rodrigues P.,Pinela J.,Dias M.I.,Fernandes I.P.,Barreiro M.F.,Morales P.,Barros L.,Ferreira I.C.F.R.
Betacyanins from Gomphrena globosa L. flowers: Incorporation in cookies as natural colouring agents
Food Chemistry, 329, , 2020

49
Sampaio S.L.,Petropoulos S.A.,Alexopoulos A.,Heleno S.A.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
Potato peels as sources of functional compounds for the food industry: A review
Trends in Food Science and Technology, 103, 118-129, 2020

50
Carocho M.,Morales P.,Ciudad-Mulero M.,Fernández-Ruiz V.,Ferreira E.,Heleno S.,Rodrigues P.,Barros L.,Ferreira I.C.F.R.
Comparison of different bread types: Chemical and physical parameters
Food Chemistry, 310, , 2020

51
Fernandes F.A.,Carocho M.,Heleno S.A.,Rodrigues P.,Dias M.I.,Pinela J.,Prieto M.A.,Simal-Gandara J.,Barros L.,Ferreira I.C.F.R.
Effect of natural preservatives on the nutritional profile, chemical composition, bioactivity and stability of a nutraceutical preparation of aloe arborescens
Antioxidants, 9, , 2020

52
Martins N.,Heleno S.A.,Ferreira I.C.F.R.
An upcoming approach to alzheimer's disease: Ethnopharmacological potential of plant bioactive molecules
Current Medicinal Chemistry, 27, 4344-4371, 2020

53
Corrêa R.C.G.,Heleno S.A.,Alves M.J.,Ferreira I.C.F.R.
Bacterial resistance: antibiotics of last generation used in clinical practice and the arise of natural products as new therapeutic alternatives
Current Pharmaceutical Design, 26, 815-837, 2020

54
Molina A.K.,Vega E.N.,Pereira C.,Dias M.I.,Heleno S.A.,Rodrigues P.,Fernandes I.P.,Barreiro M.F.,Kostić M.,Soković M.,Barreira J.C.M.,Barros L.,Ferreira I.C.F.R.
Promising antioxidant and antimicrobial food colourants from Lonicera caerulea L. var. Kamtschatica
Antioxidants, 8, , 2019

55
Rached W.,Barros L.,Ziani B.E.C.,Bennaceur M.,Calhelha R.C.,Heleno S.A.,Alves M.J.,Marouf A.,Ferreira I.C.F.R.
HPLC-DAD-ESI-MS/MS screening of phytochemical compounds and the bioactive properties of different plant parts of: Zizyphus lotus (L.) Desf.
Food and Function, 10, 5898-5909, 2019

56
Taofiq O.,Heleno S.A.,Calhelha R.C.,Fernandes I.P.,Alves M.J.,Barros L.,González-Paramás A.M.,Ferreira I.C.F.R.,Barreiro M.F.
Phenolic acids, cinnamic acid, and ergosterol as cosmeceutical ingredients: Stabilization by microencapsulation to ensure sustained bioactivity
Microchemical Journal, 147, 469-477, 2019

57
Cardoso R.V.C.,Fernandes Â.,Heleno S.A.,Rodrigues P.,Gonzaléz-Paramás A.M.,Barros L.,Ferreira I.C.F.R.
Physicochemical characterization and microbiology of wheat and rye flours
Food Chemistry, 280, 123-129, 2019

58
Mandim F.,Barros L.,Heleno S.,Pires T.,Dias M.,Alves M.,Santos P.,Ferreira I.
Phenolic profile and effects of acetone fractions obtained from the inflorescences of: Calluna vulgaris (L.) Hull on vaginal pathogenic and non-pathogenic bacteria
Food and Function, 10, 2399-2407, 2019

59
Carocho M.,Heleno S.,Rodrigues P.,Barreiro M.F.,Barros L.,Ferreira I.C.F.R.
A novel natural coating for food preservation: Effectiveness on microbial growth and physicochemical parameters
LWT, 104, 76-83, 2019

60
Rudke A.R.,Heleno S.A.,Fernandes I.P.,Prieto M.A.,Gonçalves O.H.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Microencapsulation of ergosterol and Agaricus bisporus L. extracts by complex coacervation using whey protein and chitosan: Optimization study using response surface methodology
LWT, 103, 228-237, 2019

61
Ziani B.E.C.,Heleno S.A.,Bachari K.,Dias M.I.,Alves M.J.,Barros L.,Ferreira I.C.F.R.
Phenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne
Food Research International, 116, 312-319, 2019

62
Da Silva R.,Barreira J.,Heleno S.,Barros L.,Calhelha R.,Ferreira I.
Anthocyanin profile of elderberry juice: A natural-based bioactive colouring ingredient with potential food application
Molecules, 24, , 2019

63
Mandim F.,Barros L.,Calhelha R.,Abreu R.,Pinela J.,Alves M.,Heleno S.,Santos P.,Ferreira I.
Calluna vulgaris (L.) Hull: Chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota
Food and Function, 10, 78-89, 2019

64
Taofiq O.,Heleno S.A.,Calhelha R.C.,Fernandes I.P.,Alves M.J.,Barros L.,González-Paramás A.M.,Ferreira I.C.F.R.,Barreiro M.F.
Mushroom-based cosmeceutical ingredients: Microencapsulation and in vitro release profile
Industrial Crops and Products, 124, 44-52, 2018

65
Almeida H.H.S.,Barros L.,Barreira J.C.M.,Calhelha R.C.,Heleno S.A.,Sayer C.,Miranda C.G.,Leimann F.V.,Barreiro M.F.,Ferreira I.C.F.R.
Bioactive evaluation and application of different formulations of the natural colorant curcumin (E100) in a hydrophilic matrix (yogurt)
Food Chemistry, 261, 224-232, 2018

66
Halla N.,Heleno S.A.,Costa P.,Fernandes I.P.,Calhelha R.C.,Boucherit K.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Chemical profile and bioactive properties of the essential oil isolated from Ammodaucus leucotrichus fruits growing in Sahara and its evaluation as a cosmeceutical ingredient
Industrial Crops and Products, 119, 249-254, 2018

67
Francisco C.R.L.,Heleno S.A.,Fernandes I.P.M.,Barreira J.C.M.,Calhelha R.C.,Barros L.,Gonçalves O.H.,Ferreira I.C.F.R.,Barreiro M.F.
Functionalization of yogurts with Agaricus bisporus extracts encapsulated in spray-dried maltodextrin crosslinked with citric acid
Food Chemistry, 245, 845-853, 2018

68
Villavicencio A.L.C.H.,Heleno S.A.,Calhelha R.C.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
The influence of electron beam radiation in the nutritional value, chemical composition and bioactivities of edible flowers of Bauhinia variegata L. var. candida alba Buch.-Ham from Brazil
Food Chemistry, 241, 163-170, 2018

69
Rached W.,Zeghada F.Z.,Bennaceur M.,Barros L.,Calhelha R.C.,Heleno S.,Alves M.J.,Carvalho A.M.,Marouf A.,Ferreira I.C.F.R.
Phytochemical analysis and assessment of antioxidant, antimicrobial, anti-inflammatory and cytotoxic properties of Tetraclinis articulata (Vahl) Masters leaves
Industrial Crops and Products, 112, 460-466, 2018

70
Halla N.,Fernandes I.P.,Heleno S.A.,Costa P.,Boucherit-Otmani Z.,Boucherit K.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Cosmetics preservation: A review on present strategies
Molecules, 23, , 2018

71
Oludemi T.,Barros L.,Prieto M.A.,Heleno S.A.,Barreiro M.F.,Ferreira I.C.F.R.
Extraction of triterpenoids and phenolic compounds from: Ganoderma lucidum: Optimization study using the response surface methodology
Food and Function, 9, 209-226, 2018

72
Ziani B.E.C.,Barros L.,Boumehira A.Z.,Bachari K.,Heleno S.A.,Alves M.J.,Ferreira I.C.F.R.
Profiling polyphenol composition by HPLC-DAD-ESI/MSn and the antibacterial activity of infusion preparations obtained from four medicinal plants
Food and Function, 9, 149-159, 2018

73
Taofiq O.,Heleno S.A.,Calhelha R.C.,Alves M.J.,Barros L.,González-Paramás A.M.,Barreiro M.F.,Ferreira I.C.F.R.
The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits
Food and Chemical Toxicology, 108, 139-147, 2017

74
Rached W.,Bennaceur M.,Barros L.,Calhelha R.C.,Heleno S.,Alves M.J.,Carvalho A.M.,Marouf A.,Ferreira I.C.F.R.
Detailed phytochemical characterization and bioactive properties of: Myrtus nivelii Batt & Trab
Food and Function, 8, 3111-3119, 2017

75
Ferreira I.C.F.R.,Fernandes Â.,Heleno S.A.
Chemical, nutritional, and bioactive potential of mushrooms
Edible and Medicinal Mushrooms: Technology and Applications, 455-501, 2017

76
Svobodova B.,Barros L.,Sopik T.,Calhelha R.C.,Heleno S.,Alves M.J.,Walcott S.,Kuban V.,Ferreira I.C.F.R.
Non-edible parts of Solanum stramoniifolium Jacq.-a new potent source of bioactive extracts rich in phenolic compounds for functional foods
Food and Function, 8, 2013-2021, 2017

77
Svobodova B.,Barros L.,Calhelha R.C.,Heleno S.,Alves M.J.,Walcott S.,Bittova M.,Kuban V.,Ferreira I.C.F.R.
Bioactive properties and phenolic profile of Momordica charantia L. medicinal plant growing wild in Trinidad and Tobago
Industrial Crops and Products, 95, 365-373, 2017

78
Heleno S.A.,Rudke A.R.,Calhelha R.C.,Carocho M.,Barros L.,Gonçalves O.H.,Barreiro M.F.,Ferreira I.C.F.R.
Development of dairy beverages functionalized with pure ergosterol and mycosterol extracts: An alternative to phytosterol-based beverages
Food and Function, 8, 103-110, 2017

79
Antonio A.L.,Pereira E.,Pinela J.,Heleno S.,Pereira C.,Ferreira I.C.F.R.
Determination of antioxidant compounds in foodstuff
Food Safety: Innovative Analytical Tools for Safety Assessment, 179-220, 2016

80
Taofiq O.,Heleno S.A.,Calhelha R.C.,Alves M.J.,Barros L.,Barreiro M.F.,González-Paramás A.M.,Ferreira I.C.F.R.
Development of Mushroom-Based cosmeceutical formulations with Anti-Inflammatory, Anti-Tyrosinase, antioxidant, and antibacterial properties
Molecules, 21, , 2016

81
Heleno S.A.,Prieto M.A.,Barros L.,Rodrigues A.,Barreiro M.F.,Ferreira I.C.F.R.
Optimization of microwave-assisted extraction of ergosterol from Agaricus bisporus L. by-products using response surface methodology
Food and Bioproducts Processing, 100, 25-35, 2016

82
Heleno S.A.,Diz P.,Prieto M.A.,Barros L.,Rodrigues A.,Barreiro M.F.,Ferreira I.C.F.R.
Optimization of ultrasound-assisted extraction to obtain mycosterols from Agaricus bisporus L. by response surface methodology and comparison with conventional Soxhlet extraction
Food Chemistry, 197, 1054-1063, 2016

83
Taofiq O.,Calhelha R.,Heleno S.,Barros L.,Martins A.,Santos-Buelga C.,Queiroz M.,Ferreira I.
The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: Screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives
Food Research International, 76, 821-827, 2015

84
Heleno S.A.,Barros L.,Martins A.,Morales P.,Fernández-Ruiz V.,Glamoclija J.,Sokovic M.,Ferreira I.C.F.R.
Nutritional value, bioactive compounds, antimicrobial activity and bioaccessibility studies with wild edible mushrooms
LWT, 63, 799-806, 2015

85
Heleno S.A.,Ferreira R.C.,Antonio A.L.,Queiroz M.J.R.P.,Barros L.,Ferreira I.C.F.R.
Nutritional value, bioactive compounds and antioxidant properties of three edible mushrooms from Poland
Food Bioscience, 11, 48-55, 2015

86
Heleno S.A.,Barros L.,Martins A.,Queiroz M.J.R.P.,Morales P.,Fernández-Ruiz V.,Ferreira I.C.F.R.
Chemical composition, antioxidant activity and bioaccessibility studies in phenolic extracts of two Hericium wild edible species
LWT, 63, 475-481, 2015

87
Ferreira I.C.F.R.,Heleno S.A.,Reis F.S.,Stojkovic D.,Queiroz M.J.R.P.,Vasconcelos M.H.,Sokovic M.
Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
Phytochemistry, 114, 38-55, 2015

88
Heleno S.,Martins A.,Queiroz M.,Ferreira I.
Bioactivity of phenolic acids: Metabolites versus parent compounds: A review
Food Chemistry, 173, 501-513, 2015

89
Heleno S.A.,Ferreira I.C.F.R.,Ćirić A.,Glamočlija J.,Martins A.,Queiroz M.J.R.P.,Soković M.
Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents
Food and Function, 5, 2521-2528, 2014

90
Heleno S.,Ferreira I.,Calhelha R.,Esteves A.,Martins A.,Queiroz M.
Cytotoxicity of Coprinopsis atramentaria extract, organic acids and their synthesized methylated and glucuronate derivatives
Food Research International, 55, 170-175, 2014

91
Heleno S.,Ferreira I.,Esteves A.,Ćirić A.,Glamočlija J.,Martins A.,Soković M.,Queiroz M.
Antimicrobial and demelanizing activity of Ganoderma lucidum extract, p-hydroxybenzoic and cinnamic acids and their synthetic acetylated glucuronide methyl esters
Food and Chemical Toxicology, 58, 95-100, 2013

92
Heleno S.,Stojković D.,Barros L.,Glamočlija J.,Soković M.,Martins A.,Queiroz M.,Ferreira I.
A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia
Food Research International, 51, 236-243, 2013

93
Heleno S.,Barros L.,Martins A.,Queiroz M.,Santos-Buelga C.,Ferreira I.
Phenolic, polysaccharidic, and lipidic fractions of mushrooms from northeastern portugal: Chemical compounds with antioxidant properties
Journal of Agricultural and Food Chemistry, 60, 4634-4640, 2012

94
95
Reis F.,Heleno S.,Barros L.,Sousa M.,Martins A.,Santos-Buelga C.,Ferreira I.
Toward the Antioxidant and Chemical Characterization of Mycorrhizal Mushrooms from Northeast Portugal
Journal of Food Science, 76, , 2011

96
Grangeia C.,Heleno S.,Barros L.,Martins A.,Ferreira I.
Effects of trophism on nutritional and nutraceutical potential of wild edible mushrooms
Food Research International, 44, 1029-1035, 2011

97
Heleno S.A.,Barros L.,Sousa M.J.,Martins A.,Santos-Buelga C.,Ferreira I.C.F.R.
Targeted metabolites analysis in wild Boletus species
LWT, 44, 1343-1348, 2011

98
Vaz J.,Heleno S.,Martins A.,Almeida G.,Vasconcelos M.,Ferreira I.
Wild mushrooms Clitocybe alexandri and Lepista inversa: In vitro antioxidant activity and growth inhibition of human tumour cell lines
Food and Chemical Toxicology, 48, 2881-2884, 2010

99
Heleno S.,Barros L.,Sousa M.,Martins A.,Ferreira I.
Tocopherols composition of Portuguese wild mushrooms with antioxidant capacity
Food Chemistry, 119, 1443-1450, 2010

100
Barros L.,Heleno S.A.,Carvalho A.M.,Ferreira I.C.F.R.
Lamiaceae often used in Portuguese folk medicine as a source of powerful antioxidants: Vitamins and phenolics
LWT, 43, 544-550, 2010

101
102
Barros L.,Heleno S.,Carvalho A.,Ferreira I.
Systematic evaluation of the antioxidant potential of different parts of Foeniculum vulgare Mill. from Portugal
Food and Chemical Toxicology, 47, 2458-2464, 2009

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