Polytechnic Institute
of Bragança



CIMO - Mountain Research Center. See video HERE


Pedro Jorge Louro Crugeira

Junior Researcher
Group: Socio-Ecological Systems
Supervisor: Maria Filomena Filipe Barreiro
ORCID: 0000-0002-7084-3711
Scopus Author ID: 57195309803


  • 2020 - 2021: Postdoctoral Research entitled “Photo-biostimulation Strategies for Produced Water Exopolysaccharide Production for Application in Advanced Microbiological Oil Recovery” (UFBA/CNPQ)
  • 2019 - 2021: Postdoctoral Research entitled “Sustainable biotechnological alternatives to increase the oil recovery factor of carbonate reservoirs” (UFBA/Petrogal)
  • Since 2019: Reviewer of the journals of Photochemistry and Photobiology (Biology) and Journal of Applied Microbiology
  • 2017 - 2018: Assistant professor of higher education – Salvador University Center (UNICEUSA)
  • 2015 - 2021: Consulting/research of new products – Guirré Cosmetics, industry, research, development of cosmetics (Goiânia – Brazil)
  • 2015 - 2021: Assistant professor of higher education – São Salvador College (CAELIS)
  • 2015 - 2016: Coordinator of conservation, education and environmental sanitation units - City Hall of Mata de São João.
  • 2011 - 2015: Vice coordinator of the environment nucleus – City Hall of Mata de São João


  • 2019 - PhD in Federal University of Bahia, Northeast Biotechnology Network Program (RENORBIO);
  • 2015 - Master degree in Federal University of Bahia, Biotechnology Postgraduate Program (PpgBiotec);
  • 2007 - First degree in Lusophone University of Humanities and Technologies (ULHT).


  • Study and development of bioprocesses
  • Photo-biomodulation of biological processes
  • Characterization of polymeric materials
  • Management of organic waste through catabolic or anabolic microbial or photodynamic processes, actively intervening in the circular economy
  • Recovery of natural resources through biotechnological processes
  • Development of antimicrobial therapeutic processes by Photodynamic Therapy
  • Study of photo-biomodulation processes for tissue repair


OleaChain - Skills for sustainability and innovation in the value chain of traditional olive groves in the Northern Interior of Portugal
Funding body: NORTE 2020
Reference: NORTE-06-3559-FSE-000188
Principal Investigator:José Alberto Cardoso Pereira
Start: 2021-03-01
End: 2023-11-30
RARISS - Raças Autóctones, Rastreabilidade, Inovação e Soluções Sustentáveis
Funding body: Sistemas de Incentivos à Investigação e Desenvolvimento Tecnológico (SI&DT)–I&D empresarial – Projetos em Co-promoção, integrado no Programa Operacional Temático Competitividade e Internacionalização
Principal Investigator:Maria Filomena Barreiro
Start: 2021-01-01
End: 2023-06-30

Total results: 24
Crugeira P.J.L.,Almeida H.H.S.,Marcet I.,Rendueles M.,Pires M.G.,Rafael H.M.,Rodrigues A.I.G.,Santamaria-Echart A.,Barreiro M.F.
Biosynthesis of antioxidant xanthan gum by Xanthomonas campestris using substrates added with moist olive pomace
Food and Bioproducts Processing, 141, 210-218, 2023

Soares L.G.P.,de Almeida C.G.,Crugeira P.J.L.,Nunes I.P.F.,da Silva A.P.L.T.,Almeida J.A.,Cangussú M.C.T.,de Almeida P.F.,Habib F.A.L.,Pinheiro A.L.B.
Photodynamic antimicrobial therapy (A-PDT) using 1,9-Dimethyl-Methylene Blue zinc chloride double salt - DMMB and λ640 ± 5ηm LED light in patients undertaking orthodontic treatment
Photodiagnosis and Photodynamic Therapy, 42, , 2023

Nunes I.P.F.,Crugeira P.J.L.,Sampaio F.J.P.,de Oliveira S.C.P.S.,Azevedo J.M.,Santos C.L.O.,Soares L.G.P.,Samuel I.D.W.,Persheyev S.,de Ameida P.F.,Pinheiro A.L.B.
Evaluation of dual application of photodynamic therapy—PDT in Candida albicans
Photodiagnosis and Photodynamic Therapy, 42, , 2023

Sampaio I.C.F.,Ferreira J.d.A.S.,Crugeira P.J.L.,da Silva Oliveira I.M.,dos Santos J.N.,Matos J.B.T.L.,Pinheiro A.L.B.,de Almeida P.F.
Oilfield Carbonated Produced Water Recycling Coupled to Exopolysaccharide Transformation by Lelliottia amnigena
Waste and Biomass Valorization, , 2023

Crugeira P.J.L.,Almeida H.H.S.,Teixeira L.G.,Barreiro M.F.
Photodynamic inactivation of Staphylococcus aureus by ecological antibacterial solutions associating LED (ʎ 450 ± 10 nm) with curcumin and olive leaf extracts
Journal of Photochemistry and Photobiology B: Biology, 238, , 2023

Fagnani S.R.C.A.,de Oliveira S.C.P.S.,Monteiro J.S.C.,Sampaio F.J.P.,Crugeira P.J.L.,dos Santos J.N.,Pinheiro A.L.B.
Histological evaluation of skin lesions induced by Leishmania braziliensis treated by PACT using Laser light and 1.9 dimethyl-methylene blue
Photodiagnosis and Photodynamic Therapy, 38, , 2022

Sampaio I.C.F.,Jorge Louro Crugeira P.,de Azevedo Santos Ferreira J.,Nunes dos Santos J.,Borges Torres Lima Matos J.,Luiz Barbosa Pinheiro A.,Chinalia F.A.,Fernando de Almeida P.
Up-recycling oil produced water as the media-base for the production of xanthan gum
Biopolymers, 113, , 2022

Ramos de Souza E.,Rodrigues P.D.,Sampaio I.C.F.,Bacic E.,Crugeira P.J.L.,Vasconcelos A.C.,dos Santos Silva M.,dos Santos J.N.,Quintella C.M.,Pinheiro A.L.B.,Almeida P.F.d.
Xanthan gum produced by Xanthomonas campestris using produced water and crude glycerin as an environmentally friendlier agent to enhance oil recovery
Fuel, 310, , 2022

Crugeira P.J.L.,de Almeida P.F.,Sampaio I.C.F.,Soares L.G.P.,Moraga Amador D.A.,Samuel I.D.W.,Persheyev S.,Silveira L.,Pinheiro A.L.B.
Production and viscosity of Xanthan Gum are increased by LED irradiation of X. campestris cultivated in medium containing produced water of the oil industry
Journal of Photochemistry and Photobiology B: Biology, 226, , 2022

Sampaio I.C.F.,Crugeira P.J.l.,de Azevedo Santos Ferreira J.,de Almeida Santos J.,dos Santos J.N.,Ramos-de-Souza E.,Pinheiro A.L.B.,Matos J.B.T.L.,Chinalia F.A.,de Almeida P.F.
Surfactant/Alkali Stress Effect in Exopolysaccharide Production by Xanthomonas and Enterobacter Strains
Engineering Materials, 695-717, 2021

Pinheiro A.L.B.,de Almeida P.F.,Sampaio I.C.F.,Crugeira P.J.L.,dos Santos J.N.,Matos J.B.T.L.,Soares L.G.P.,Moraga Amador D.A.,Silveira L.
Effects of photo-stimulation with laser or LED on the composition of Xanthan gum produced in media containing distilled water or dialyzed or not produced water by means of Raman spectroscopy
Journal of Photochemistry and Photobiology B: Biology, 213, , 2020

Sampaio I.C.F.,Crugeira P.J.L.,Soares L.G.P.,dos Santos J.N.,de Almeida P.F.,Pinheiro A.L.B.,Silveira L.
Composition of Xanthan gum produced by Xanthomonas campestris using produced water from a carbonated oil field through Raman spectroscopy
Journal of Photochemistry and Photobiology B: Biology, 213, , 2020

Monteiro J.S.C.,Rangel E.E.,de Oliveira S.C.P.S.,Crugeira P.J.L.,Nunes I.P.F.,Sandra S.R.C.,Sampaio F.J.P.,de Almeida P.F.,Pinheiro A.L.B.
Enhancement of photodynamic inactivation of planktonic cultures of Staphylococcus aureus by DMMB-AuNPs
Photodiagnosis and Photodynamic Therapy, 31, , 2020

Correia N.A.,Batista L.T.A.,Nascimento R.J.M.,Cangussú M.C.T.,Crugeira P.J.L.,Soares L.G.P.,Silveira L.,Pinheiro A.L.B.
Detection of prostate cancer by Raman spectroscopy: A multivariate study on patients with normal and altered PSA values
Journal of Photochemistry and Photobiology B: Biology, 204, , 2020

Crugeira P.J.L.,Chinalia F.A.,Brandão H.N.,Matos J.B.T.L.,Pinheiro A.L.B.,Almeida P.F.
Effect of Light Stimulation on a Thermo-Cellulolytic Bacterial Consortium Used for the Degradation of Cellulose of Green Coconut Shells
Engineering Materials, 145-168, 2020

Pinheiro A.L.B.,Sampaio F.J.P.,Dea Santos D.,Crugeira P.J.L.,De Oliveira S.C.P.S.,Monteiro J.S.C.,Fagnani S.R.C.A.,Nunes I.P.F.,Soares L.G.P.,De Almeida P.F.
Nanoconcentrations of 1,9-dimethylmethylene blue (DMMB) associated to laser, LED or polarized light are highly effective on AmPDT carried out in aerobes and aerotolerant anaerobes Gram-positive bacteria
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 11221, , 2020

Soares L.G.P.,Crugeira P.J.L.,Nunes I.P.F.,Santos A.S.,Cangussú M.C.T.,de Almeida P.F.,Pinheiro A.L.B.,Habib F.A.L.
Oral microbiological control by photodynamic action in orthodontic patients
Photodiagnosis and Photodynamic Therapy, 28, 221-225, 2019

Sampaio F.J.P.,de Oliveira S.C.P.S.,Crugeira P.J.L.,Monteiro J.S.C.,de Araújo Fagnani S.R.C.,Pepe I.M.,de Almeida P.F.,Pinheiro A.L.B.
aPDT using nanoconcentration of 1,9-dimethylmethylene blue associated to red light is efficacious in killing Enterococcus faecalis ATCC 29212 in vitro
Journal of Photochemistry and Photobiology B: Biology, 200, , 2019

Santos D.d.A.,Crugeira P.J.L.,Nunes I.P.F.,de Almeida P.F.,Pinheiro A.L.B.
A novel technique of antimicrobial photodynamic therapy – aPDT using 1,9-dimethyl-methylene blue zinc chloride double salt-DMMB and polarized light on Staphylococcus aureus
Journal of Photochemistry and Photobiology B: Biology, 200, , 2019

Crugeira P.J.L.,Pires Santos G.M.,de Oliveira S.C.P.S.,Sampaio F.J.P.,Fagnani S.R.C.A.,Sampaio I.C.F.,de Souza Ferreira E.,Chinalia F.A.,Pinheiro A.L.B.,de Almeida P.F.
Effects of photostimulation on the catabolic process of xenobiotics
Journal of Photochemistry and Photobiology B: Biology, 191, 38-43, 2019

Santos G.M.P.,Oliveira S.C.P.S.,Monteiro J.C.S.,Fagnani S.R.,Sampaio F.P.,Correia N.A.,Crugeira P.J.L.,Pinheiro A.L.B.
ROS-induced autophagy reduces B16F10 melanoma cell proliferative activity
Lasers in Medical Science, 33, 1335-1340, 2018

Santos G.,de Oliveira S.,Monteiro J.,Fagnani S.,Sampaio F.,Crugeira P.,Almeida P.,Pinheiro A.
Effects of PACT using phenothiazine-derived drugs and red light on the macrophage x S. aureus interface
Photodiagnosis and Photodynamic Therapy, 22, 96-100, 2018

Crugeira P.J.L.,Pires-Santos G.M.,de Oliveira S.C.P.S.,Sampaio F.J.P.,Correia N.A.,Fagnani S.R.C.d.A.,Chinalia F.A.,de Almeida P.F.,Pinheiro A.L.B.
Photobiological effect of Laser or LED light in a thermophilic microbial consortium
Journal of Photochemistry and Photobiology B: Biology, 181, 115-121, 2018

de Oliveira S.,da Ordem Trahamane E.,Monteiro J.,Santos G.,Crugeira P.,Sampaio F.,Oliveira C.,Neto M.,Pinheiro A.
Leishmanicidal effect of antiparasitic photodynamic therapy—ApPDT on infected macrophages
Lasers in Medical Science, 32, 1959-1964, 2017