MOUNTAIN
RESEARCH
CENTER

Polytechnic Institute
of Bragança

image01

CIMO

CIMO - Mountain Research Center. See video HERE

FROM NATURE TO PRODUCTS, TOWARDS SUSTAINABILITY.

Sandrina Heleno

Group: Sustainable Processes and Products
Phone: 273303285
E-mail: sheleno@ipb.pt
ORCID: 000-0001-7224-1098
Scopus Author ID: 30067731800

Career

  • Since 2023: Auxiliary researcher at the Mountain Research Center of the Polytechnic Institute of Bragança (CIMO-IPB), Portugal
  • 2019 - 2023: Junior Researcher (national funding by FCT, Foundation dor Science and Tecnhology) at the Mountain Research Center of the Polytechnic Institute of Bragança (CIMO-IPB), Portugal
  • 2015 - 2019: Pos-Doc researcher (SFRH/BPD/101413/2014)
  • 2015 - 2015: Pos-Doc researcher in the project ( NORTE-07-0124-FEDER- 0000014) - Polymer Reaction Engineering, Laboratory of Separation and Reaction Engineering, at the Mountain Research Center of the Polytechnic Institute of Bragança (CIMO-IPB), Portugal

Qualifications

  • 2014 - PhD. in Sciences, speciality in chemistry, University of Minho (UM), Portugal
  • 2010 - MSc. in Biotechnology, Polytechnic Institute of Bragança (IPB), Portugal
  • 2008 - Graduation in Biotechnological Engineering, Polytechnic Institute of Bragança (IPB), Portugal

Awards and Honors

  • 2024 - “The best of the year 2023” award: Winning project in the Innovation/Research category of the year with the PreVineGrape project: Development of a biofungicide to combat grapevine diseases; Revista vinhos.
  • 2023 - Distinction – list of most cited authors, a ranking resulting from a study carried out by Stanford University (USA) - database of most cited scientists that provides standardized information on citations, h-index, hm-index adjusted for co-authorship , citations of articles in different authorship positions and a composite indicator (c-score). Career-wide data is updated to the end of 2021, and recent single-year data refers to citations during calendar year 2021. Selection is based on the top 100,000 scientists by c-score (with and without self-citations ) or a percentile rank of 2% or greater in the subfield
  • 2022 - Distinction – Integration of the 4th edition of the book Mulheres na Ciência. Centro de Ciência viva, Lisbon, Portugal
  • 2022 - Promove Program (2020-2021) - Initiative B - Ideas with the potential to become innovative pilot projects
  • 2022 - Distinction – list of most cited authors, a ranking resulting from a study carried out by Stanford University (USA) - database of most cited scientists that provides standardized information on citations, h-index, hm-index adjusted for co-authorship , citations of articles in different authorship positions and a composite indicator (c-score). Career-wide data is updated to the end of 2021, and recent single-year data refers to citations during calendar year 2021. Selection is based on the top 100,000 scientists by c-score (with and without self-citations ) or a percentile rank of 2% or greater in the subfield
  • 2019 - Distinction - Winner of the Born from Knowledge Caixa Agrícola Distinction. “ChestWine” project. Lisbon, Portugal
  • 2019 - National Award – Winner of the Caixa Agrícola Entrepreneurship and Innovation award, in the Production, Transformation and Marketing category. “ChestWine” project, Portugal
  • 2017 - Ward for the best oral communication in the VIII Fórum Ibérico de Úlceras e Feridas, Guimarães, Portugal

Interests

  • Extraction, purification and characterization of bioactive compounds
  • Development of biostimulants, biofungicides of natural origin
  • Vines and wines
  • Elicitation of mushroom´s bioactives and nutrients
  • Development of Bio-based Sport beverages
  • Functional agents for the food and beverage industries
  • Bio-based antimicrobials

Projects:

TextBlueStyle - Obtenção de corantes azuis naturais e sustentáveis para aplicação têxtil
Funding body: Promove LA CAIXA
Reference:
Principal Investigator:Manuel Ricardo Costa Calhelha
Start: 2023-07-01
End: 2026-06-30
Mush4Chol - Development of an efficient hypocholesterolemic formulation from mushroom bioresidues through a sustainable integrated strategy
Funding body: FCT - PTDC - Projectos em todos os domínios científicos
Reference: 2022.08844.PTDC
Principal Investigator:Sandrina Alves Heleno
Start: 2023-03-01
End: 2026-02-28
WOODLANDFUNGI - Valorização e Sustentabilidade dos Cogumelos Silvestres do Barroso
Funding body: Promove LA CAIXA
Reference:
Principal Investigator:Carla Susana Correia Pereira
Start: 2023-06-30
End: 2025-05-31
PulpIng - Development of Pumpking Pulp Formulations using a Sustainable Integrated Strategy
Funding body: PRIMA
Reference: PRIMA/0007/2019
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-09-01
End: 2024-08-31
Aquavitae - Thermal water as a source of life and health
Funding body: Promove LA CAIXA
Reference: PD20-00003
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-09-01
End: 2024-05-31
WASTESILK - Silk Sericin as an industrial wastewater with valuable biomedical potential
Funding body: FCT - PTDC - Projectos em todos os domínios científicos
Reference: PTDC/BTA-BTA/0696/2020
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-03-29
End: 2024-03-28
RevestCAST - Otimização dos processos industriais de aplicação de revestimentos comestíveis para a conservação pós-colheita da castanha (Castanea sativa)
Funding body: PORTUGAL 2020 - COMPETE 2020 - Programa Operacional Competitividade e Internacionalização
Reference: POCI-01-0247-FEDER-049276
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-01-31
End: 2023-06-30
Bio4drinks - Obtenção de Ingredientes Naturais Multifuncionais para a Indústria de Bebidas
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-0247-FEDER-113508
Principal Investigator:Sandrina Alves Heleno
Start: 2021-09-01
End: 2023-06-30
100%FIGO - Produto biofuncional e com elevada eficiência de circularidade na transformação e conservação por tecnologias avançadas de extração e incorporação de compostos bioativos
Funding body: PORTUGAL 2020 - COMPETE 2020 - Programa Operacional Competitividade e Internacionalização
Reference: POCI-01-0247-FEDER-064977
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-01-01
End: 2023-06-29
PreVineGrape - Desenvolvimento de um biofungicida para combate a doenças da videira
Funding body: PORTUGAL 2020 - COMPETE 2020 - Programa Operacional Competitividade e Internacionalização
Reference: POCI-01-0247-FEDER-049695
Principal Investigator:Sandrina Alves Heleno
Start: 2021-01-01
End: 2023-06-29
VALORNATURAL - Valorização de Recursos Naturais através da Extração de Ingredientes de Elevado Valor Acrescentado para Aplicações na Indústria Alimentar
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-0247-FEDER-024479
Principal Investigator:Lillian Bouçada de Barros
Start: 2018-09-01
End: 2022-08-31
SpraySafe - Proteção de Direitos de Propriedade Intelectual relativos à "obtenção de uma solução de imersão a partir de extratos de Rosmarinus officinalis L. para utilização como revestimento alimentar"
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-0145-FEDER-044060
Principal Investigator:Lillian Bouçada de Barros
Start: 2019-07-01
End: 2022-06-30
PlantCovid - Aplicações de extratos de plantas com ação dirigida ao SARS-CoV-2
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-02B/-FEDER-054870
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-07-14
End: 2021-12-31
Halófitas Vermelhas - Halófitas vermelhas como nova fonte de biomoléculas com aplicação na indústria alimentar, nutracêutica e medicina
Funding body: Programa bilateral Portugal/Tunísia
Reference:
Principal Investigator:João Carlos Martins Barreira
Start: 2019-01-01
End: 2020-12-31

Total results: 113
1
2
Mandim F.,Petropoulos S.A.,Pinto C.A.,Heleno S.A.,Rodrigues P.,Dias M.I.,Saraiva J.A.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.,Pinela J.
Novel cold and thermally pasteurized cardoon-enriched functional smoothie formulations: A zero-waste manufacturing approach
Food Chemistry, 456, , 2024

3
Pires L.,González-Paramás A.M.,Heleno S.A.,Calhelha R.C.
Exploring Therapeutic Advances: A Comprehensive Review of Intestinal Microbiota Modulators
Antibiotics, 13, , 2024

4
Fernandes F.A.,Carocho M.,Prieto M.A.,Barros L.,Ferreira I.C.F.R.,Heleno S.A.
Nutraceuticals and dietary supplements: balancing out the pros and cons
Food and Function, 15, 6289-6303, 2024

5
Pires L.,González-Paramás A.M.,Heleno S.A.,Calhelha R.C.
The Role of Gut Microbiota in the Etiopathogenesis of Multiple Chronic Diseases
Antibiotics, 13, , 2024

6
7
Sosa D.,Alves F.M.,Prieto M.A.,Pedrosa M.C.,Heleno S.A.,Barros L.,Feliciano M.,Carocho M.
Lemna minor: Unlocking the Value of This Duckweed for the Food and Feed Industry
Foods, 13, , 2024

8
de Oliveira I.,Chrysargyris A.,Finimundy T.C.,Carocho M.,Santos-Buelga C.,Calhelha R.C.,Tzortzakis N.,Barros L.,Heleno S.A.
Magnesium and manganese induced changes on chemical, nutritional, antioxidant and antimicrobial properties of the pansy and Viola edible flowers
Food Chemistry, 438, , 2024

9
da Silveira T.F.F.,Hasni J.,Portelada N.,Fernandes F.A.,Rodrigues P.,Lemos A.,Ferreira I.C.F.R.,Alves M.J.,Barros L.,Heleno S.A.
Development and characterisation of gluten-free fresh pasta using teff, rice, and buckwheat flours enhanced with thermal waters: a mixture design approach
International Journal of Food Science and Technology, , 2024

10
Plasencia P.,Finimundy T.C.,Carocho M.,Calhelha R.C.,Añibarro-Ortega M.,Pires T.C.S.P.,Barreiro F.,Garcia P.A.,Barros L.,Heleno S.A.
Extraction of Bioactive Compounds from Rubus Idaeus Bioresidues: A Full Screening on Phenolic Composition and Bioactive Potential
Waste and Biomass Valorization, , 2024

11
Pedrosa M.C.,Ueda J.M.,Heleno S.A.,Carocho M.,Reis F.S.,Ferreira I.C.F.R.,Barros L.
Value-Added Lipids from Plant Foods and Respective Applications
Food Byproducts Management and Their Utilization, 91-126, 2024

12
Chtioui W.,Heleno S.,Migheli Q.,Rodrigues P.
Plant extracts as biocontrol agents against Aspergillus carbonarius growth and ochratoxin A production in grapes
International Journal of Food Microbiology, 407, , 2023

13
Ueda J.M.,Morales P.,Fernández-Ruiz V.,Ferreira A.,Barros L.,Carocho M.,Heleno S.A.
Powdered Foods: Structure, Processing, and Challenges: A Review
Applied Sciences (Switzerland), 13, , 2023

14
Ueda J.M.,Griebler K.R.,Finimundy T.C.,Rodrigues D.B.,Veríssimo L.,Pires T.C.S.P.,Gonçalves J.,Fernandes I.P.,Pereira E.,Barros L.,Heleno S.A.,Calhelha R.C.
Polyphenol Composition by HPLC-DAD-(ESI-)MS/MS and Bioactivities of Extracts from Grape Agri-Food Wastes
Molecules, 28, , 2023

15
Albuquerque B.R.,Pinela J.,Pereira C.,Mandim F.,Heleno S.,Oliveira M.B.P.P.,Barros L.
Recovery of anthocyanins from Eugenia spp. fruit peels: a comparison between heat- and ultrasound-assisted extraction
Sustainable Food Technology, 2, 189-201, 2023

16
Plasencia P.,Heleno S.A.,Finimundy T.,Carocho M.,Calhelha R.C.,Añibarro-Ortega M.,Alves M.J.,Oludemi T.,Quidiongo N.,Barreiro F.,García P.A.,Ferreira I.C.F.R.,Barros L.
Recovery of High Valuable Bioactive Molecules from Vaccinium myrtillus L. Bioresidues
Waste and Biomass Valorization, 14, 2873-2884, 2023

17
Roriz C.L.,Carocho M.,Alves M.J.,Rodrigues P.,Morales P.,Ferreira I.C.F.R.,Heleno S.A.,Barros L.
Betacyanins obtained from alternative novel sources as natural food colorant additives: incorporated in savory and sweet food products
Food and Function, 14, 8775-8784, 2023

18
Martins de Deus B.,Fernandes C.,Molina A.K.,Xavier V.,Pires T.C.S.P.,Mandim F.,Heleno S.A.,Finimundy T.C.,Barros L.
Chemical Characterization, Bioactivity and Toxicity of European Flora Plant Extracts in Search for Potential Natural Origin Preservatives
Plants, 12, , 2023

19
de Oliveira I.,Chrysargyris A.,Heleno S.A.,Carocho M.,Calhelha R.C.,Dias M.I.,Petrović J.,Soković M.,Petropoulos S.A.,Santos-Buelga C.,Tzortzakis N.,Barros L.
Effects of the extraction techniques on the chemical composition and bioactive properties of lemon balm (Melissa officinalis L.) plants grown under different cropping and irrigation regimes
Food Research International, 170, , 2023

20
Rodrigues D.B.,Veríssimo L.,Finimundy T.,Rodrigues J.,Oliveira I.,Gonçalves J.,Fernandes I.P.,Barros L.,Heleno S.A.,Calhelha R.C.
Chemical and Bioactive Screening of Green Polyphenol-Rich Extracts from Chestnut By-Products: An Approach to Guide the Sustainable Production of High-Added Value Ingredients
Foods, 12, , 2023

21
Inumaro R.S.,Casalvara R.F.A.,Corrêa R.C.G.,Barros L.,Pereira C.,Calhelha R.M.,Heleno S.A.,Pimentel T.C.,Gonçalves J.E.,Cardozo-Filho L.
Supercritical fluid-assisted extraction of hop cone residue from craft breweries
Journal of CO2 Utilization, 72, , 2023

22
Castillo A.,Finimundy T.C.,Heleno S.A.,Rodrigues P.,Fernandes F.A.,Pereira S.,Lores M.,Barros L.,Garcia-Jares C.
The generally recognized as safe (GRAS) microalgae Haematococcus pluvialis (wet) as a multifunctional additive for coloring and improving the organoleptic and functional properties of foods
Food and Function, 14, 6023-6035, 2023

23
Mediavilla I.,Bados R.,Barros L.,Xavier V.,Finimundy T.C.,Pires T.C.S.P.,Heleno S.A.,Calhelha R.C.,Amaral J.S.,Rizzo A.M.,Casini D.,Lombardi G.,Chiaramonti D.,Cámara M.,Suárez A.,Ardid T.,Esteban L.S.
Assessment of the Use of Common Juniper (Juniperus communis L.) Foliage following the Cascade Principle
Molecules, 28, , 2023

24
Shiraishi C.S.H.,Zbiss Y.,Roriz C.L.,Dias M.I.,Prieto M.A.,Calhelha R.C.,Alves M.J.,Heleno S.A.,da Cunha Mendes V.,Carocho M.,Abreu R.M.V.,Barros L.
Fig Leaves (Ficus carica L.): Source of Bioactive Ingredients for Industrial Valorization
Processes, 11, , 2023

25
26
Carocho M.,Heleno S.A.,Barros L.
Natural Secondary Metabolites: From Nature, Through Science, to Industry
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 1-965, 2023

27
Hached H.,Cassani L.,Zbiss Y.,Fraga-Corral M.,Oliveira I.,Pereira A.G.,Prieto M.A.,Heleno S.A.,Carocho M.
Non-alkaloid nitrogen-containing compounds from fungi
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 627-646, 2023

28
Liberal Â.,Cardoso R.V.C.,Heleno S.A.,Fernandes Â.,Barros L.,Martins A.
Phenolic Acids from Fungi
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 475-495, 2023

29
de Oliveira I.,Albuquerque B.,Ueda J.M.,Alves M.J.,Ferreira I.C.F.R.,Barros L.,Heleno S.A.
New challenges and opportunities from secondary metabolites
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 925-965, 2023

30
Carocho M.,Heleno S.A.,Barros L.
Preface
Natural Secondary Metabolites: From Nature, Through Science, to Industry, v, 2023

31
Xavier V.,Spréa R.,Finimundy T.C.,Heleno S.A.,Amaral J.S.,Barros L.,Ferreira I.C.F.R.
Terpenes
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 107-156, 2023

32
Calhelha R.C.,Haddad H.,Ribeiro L.,Heleno S.A.,Carocho M.,Barros L.
Inflammation: What’s There and What’s New?
Applied Sciences (Switzerland), 13, , 2023

33
Heleno S.A.,Carocho M.,Reis F.S.,Pires T.C.S.P.,Pintado M.,Ferreira I.C.F.R.,Barros L.
Plant Extracts and SARS-CoV-2: Research and Applications
Life, 13, , 2023

34
Albuquerque B.R.,Pinela J.,Pereira C.,Calhelha R.C.,Oliveira I.,Heleno S.,Oliveira M.B.P.P.,Barros L.
Optimization and comparison of heat- and ultrasound-assisted extraction methods for anthocyanin recovery from Sicana odorifera fruit epicarp
Biomass Conversion and Biorefinery, , 2023

35
Barros L.,Heleno S.A.,Prieto M.A.
Natural Products as Health Promoters
Current Pharmaceutical Design, 29, 803, 2023

36
Ueda J.M.,Milho C.,Heleno S.A.,Soria-Lopez A.,Carpena M.,Alves M.J.,Pires T.,Prieto M.A.,Simal-Gandara J.,Calhelha R.C.,Ferreira I.C.F.R.,Barros L.
Emerging Strategies to Combat Methicillin-resistant Staphylococcus aureus (MRSA): Natural Agents with High Potential
Current Pharmaceutical Design, 29, 837-851, 2023

37
Zaier M.M.,Heleno S.A.,Mandim F.,Calhelha R.C.,Ferreira I.C.F.R.,Achour L.,Kacem A.,Dias M.I.,Barros L.
Effects of the seasonal variation in the phytochemical composition and bioactivities of the wild halophyte Suaeda fruticosa
Food Bioscience, 50, , 2022

38
Durazzo A.,Carocho M.,Heleno S.A.,Pedrosa M.C.,Ueda J.M.,Barros L.,Souto E.B.,Santini A.,Lucarini M.
Fermented food/beverage and health: current perspectives
Rendiconti Lincei, 33, 729-738, 2022

39
de la Fuente B.,Pinela J.,Calhelha R.C.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Sea bass (Dicentrarchus labrax) and sea bream (Sparus aurata) head oils recovered by microwave-assisted extraction: Nutritional quality and biological properties
Food and Bioproducts Processing, 136, 97-105, 2022

40
Polyzos N.,Paschoalinotto B.H.,Compocholi M.,Pinela J.,Heleno S.A.,Calhelha R.C.,Dias M.I.,Barros L.,Petropoulos S.A.
Fertilization of Pot-Grown Cichorium spinosum L.: How It Can Affect Plant Growth, Chemical Profile, and Bioactivities of Edible Parts?
Horticulturae, 8, , 2022

41
Durazzo A.,Carocho M.,Heleno S.,Barros L.,Souto E.B.,Santini A.,Lucarini M.
Food dyes and health: Literature quantitative research analysis
Measurement: Food, 7, , 2022

42
Alonso-Esteban J.I.,Carocho M.,Barros D.,Velho M.V.,Heleno S.,Barros L.
Chemical composition and industrial applications of Maritime pine (Pinus pinaster Ait.) bark and other non-wood parts
Reviews in Environmental Science and Biotechnology, 21, 583-633, 2022

43
de la Fuente B.,Pinela J.,Mandim F.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Nutritional and bioactive oils from salmon (Salmo salar) side streams obtained by Soxhlet and optimized microwave-assisted extraction
Food Chemistry, 386, , 2022

44
Fernandes F.A.,Pedrosa M.C.,Ueda J.M.,Ferreira E.,Rodrigues P.,Heleno S.A.,Carocho M.,Prieto M.A.,Ferreira I.C.F.R.,Barros L.
Improving the physicochemical properties of a traditional Portuguese cake - “económicos” with chestnut flour
Food and Function, 13, 8243-8253, 2022

45
Fernandes F.A.,Heleno S.A.,Pinela J.,Carocho M.,Prieto M.A.,Ferreira I.C.F.R.,Barros L.
Recovery of Citric Acid from Citrus Peels: Ultrasound-Assisted Extraction Optimized by Response Surface Methodology
Chemosensors, 10, , 2022

46
Ueda J.M.,Pedrosa M.C.,Heleno S.A.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Food Additives from Fruit and Vegetable By-Products and Bio-Residues: A Comprehensive Review Focused on Sustainability
Sustainability (Switzerland), 14, , 2022

47
Derbassi N.B.,Pedrosa M.C.,Heleno S.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Plant volatiles: Using Scented molecules as food additives
Trends in Food Science and Technology, 122, 97-103, 2022

48
Roriz C.L.,Heleno S.A.,Alves M.J.,Oliveira M.B.P.P.,Pinela J.,Dias M.I.,Calhelha R.C.,Morales P.,Ferreira I.C.F.R.,Barros L.
Red pitaya (Hylocereus costaricensis) peel as a source of valuable molecules: Extraction optimization to recover natural colouring agents
Food Chemistry, 372, , 2022

49
Derbassi N.,C. Pedrosa M.,Heleno S.,Fernandes F.,Dias M.I.,Calhelha R.C.,Rodrigues P.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Arbutus unedo leaf extracts as potential dairy preservatives: case study on quark cheese
Food and Function, , 2022

50
Xavier V.,Finimundy T.C.,Heleno S.A.,Amaral J.S.,Calhelha R.C.,Vaz J.,Pires T.C.S.P.,Mediavilla I.,Esteban L.S.,Ferreira I.C.F.R.,Barros L.
Chemical and bioactive characterization of the essential oils obtained from three mediterranean plants
Molecules, 26, , 2021

51
Pedrosa M.C.,Lima L.,Heleno S.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Food metabolites as tools for authentication, processing, and nutritive value assessment
Foods, 10, , 2021

52
Vega E.N.,Molina A.K.,Pereira C.,Dias M.I.,Heleno S.A.,Rodrigues P.,Fernandes I.P.,Barreiro M.F.,Stojković D.,Soković M.,Carocho M.,Barreira J.C.M.,Ferreira I.C.F.R.,Barros L.
Anthocyanins from rubus fruticosus l. And morus nigra l. applied as food colorants: A natural alternative
Plants, 10, , 2021

53
Ceccanti C.,Finimundy T.C.,Heleno S.A.,Pires T.C.S.P.,Calhelha R.C.,Guidi L.,Ferreira I.C.F.R.,Barros L.
Differences in the phenolic composition and nutraceutical properties of freeze dried and oven-dried wild and domesticated samples of Sanguisorba minor Scop
LWT, 145, , 2021

54
Roriz C.L.,Xavier V.,Heleno S.A.,Pinela J.,Dias M.I.,Calhelha R.C.,Morales P.,Ferreira I.C.F.R.,Barros L.
Chemical and bioactive features of amaranthus caudatus l. Flowers and optimized ultrasound-assisted extraction of betalains
Foods, 10, , 2021

55
Ueda J.M.,Pedrosa M.C.,Fernandes F.A.,Rodrigues P.,Melgar B.,Dias M.I.,Pinela J.,Calhelha R.C.,Ivanov M.,Soković M.,Heleno S.A.,Carocho M.,Ineu R.P.,Ferreira I.C.F.R.,Barros L.
Promising preserving agents from sage and basil: A case study with yogurts
Foods, 10, , 2021

56
Gómez-Mejía E.,Roriz C.L.,Heleno S.A.,Calhelha R.,Dias M.I.,Pinela J.,Rosales-Conrado N.,León-González M.E.,Ferreira I.C.F.R.,Barros L.
Valorisation of black mulberry and grape seeds: Chemical characterization and bioactive potential
Food Chemistry, 337, , 2021

57
Albuquerque B.R.,Heleno S.A.8.,Oliveira M.B.P.P.,Barros L.,Ferreira I.C.F.R.
Phenolic compounds: Current industrial applications, limitations and future challenges
Food and Function, 12, 14-29, 2021

58
Pedrosa M.C.,Ueda J.M.,Melgar B.,Dias M.I.,Pinela J.,Calhelha R.C.,Ivanov M.,Soković M.,Heleno S.,da Silva A.B.,Carocho M.,Ferreira I.C.F.R.,Barros L.
Preservation of chocolate muffins with Lemon Balm, Oregano, and Rosemary extracts
Foods, 10, , 2021

59
Roriz C.L.,Heleno S.A.,Carocho M.,Rodrigues P.,Pinela J.,Dias M.I.,Fernandes I.P.,Barreiro M.F.,Morales P.,Barros L.,Ferreira I.C.F.R.
Betacyanins from Gomphrena globosa L. flowers: Incorporation in cookies as natural colouring agents
Food Chemistry, 329, , 2020

60
Sampaio S.L.,Petropoulos S.A.,Alexopoulos A.,Heleno S.A.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
Potato peels as sources of functional compounds for the food industry: A review
Trends in Food Science and Technology, 103, 118-129, 2020

61
Carocho M.,Morales P.,Ciudad-Mulero M.,Fernández-Ruiz V.,Ferreira E.,Heleno S.,Rodrigues P.,Barros L.,Ferreira I.C.F.R.
Comparison of different bread types: Chemical and physical parameters
Food Chemistry, 310, , 2020

62
Fernandes F.A.,Carocho M.,Heleno S.A.,Rodrigues P.,Dias M.I.,Pinela J.,Prieto M.A.,Simal-Gandara J.,Barros L.,Ferreira I.C.F.R.
Effect of natural preservatives on the nutritional profile, chemical composition, bioactivity and stability of a nutraceutical preparation of aloe arborescens
Antioxidants, 9, , 2020

63
Martins N.,Heleno S.A.,Ferreira I.C.F.R.
An upcoming approach to alzheimer's disease: Ethnopharmacological potential of plant bioactive molecules
Current Medicinal Chemistry, 27, 4344-4371, 2020

64
Corrêa R.C.G.,Heleno S.A.,Alves M.J.,Ferreira I.C.F.R.
Bacterial resistance: antibiotics of last generation used in clinical practice and the arise of natural products as new therapeutic alternatives
Current Pharmaceutical Design, 26, 815-837, 2020

65
Molina A.K.,Vega E.N.,Pereira C.,Dias M.I.,Heleno S.A.,Rodrigues P.,Fernandes I.P.,Barreiro M.F.,Kostić M.,Soković M.,Barreira J.C.M.,Barros L.,Ferreira I.C.F.R.
Promising antioxidant and antimicrobial food colourants from Lonicera caerulea L. var. Kamtschatica
Antioxidants, 8, , 2019

66
Rached W.,Barros L.,Ziani B.E.C.,Bennaceur M.,Calhelha R.C.,Heleno S.A.,Alves M.J.,Marouf A.,Ferreira I.C.F.R.
HPLC-DAD-ESI-MS/MS screening of phytochemical compounds and the bioactive properties of different plant parts of: Zizyphus lotus (L.) Desf.
Food and Function, 10, 5898-5909, 2019

67
Taofiq O.,Heleno S.A.,Calhelha R.C.,Fernandes I.P.,Alves M.J.,Barros L.,González-Paramás A.M.,Ferreira I.C.F.R.,Barreiro M.F.
Phenolic acids, cinnamic acid, and ergosterol as cosmeceutical ingredients: Stabilization by microencapsulation to ensure sustained bioactivity
Microchemical Journal, 147, 469-477, 2019

68
Cardoso R.V.C.,Fernandes Â.,Heleno S.A.,Rodrigues P.,Gonzaléz-Paramás A.M.,Barros L.,Ferreira I.C.F.R.
Physicochemical characterization and microbiology of wheat and rye flours
Food Chemistry, 280, 123-129, 2019

69
Mandim F.,Barros L.,Heleno S.A.,Pires T.C.S.P.,Dias M.I.,Alves M.J.,Santos P.F.,Ferreira I.C.F.R.
Phenolic profile and effects of acetone fractions obtained from the inflorescences of: Calluna vulgaris (L.) Hull on vaginal pathogenic and non-pathogenic bacteria
Food and Function, 10, 2399-2407, 2019

70
Carocho M.,Heleno S.,Rodrigues P.,Barreiro M.F.,Barros L.,Ferreira I.C.F.R.
A novel natural coating for food preservation: Effectiveness on microbial growth and physicochemical parameters
LWT, 104, 76-83, 2019

71
Rudke A.R.,Heleno S.A.,Fernandes I.P.,Prieto M.A.,Gonçalves O.H.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Microencapsulation of ergosterol and Agaricus bisporus L. extracts by complex coacervation using whey protein and chitosan: Optimization study using response surface methodology
LWT, 103, 228-237, 2019

72
Ziani B.E.C.,Heleno S.A.,Bachari K.,Dias M.I.,Alves M.J.,Barros L.,Ferreira I.C.F.R.
Phenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne
Food Research International, 116, 312-319, 2019

73
Da Silva R.F.R.,Barreira J.C.M.,Heleno S.A.,Barros L.,Calhelha R.C.,Ferreira I.C.F.R.
Anthocyanin profile of elderberry juice: A natural-based bioactive colouring ingredient with potential food application
Molecules, 24, , 2019

74
Mandim F.,Barros L.,Calhelha R.C.,Abreu R.M.V.,Pinela J.,Alves M.J.,Heleno S.,Santos P.F.,Ferreira I.C.F.R.
Calluna vulgaris (L.) Hull: Chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota
Food and Function, 10, 78-89, 2019

75
Taofiq O.,Heleno S.A.,Calhelha R.C.,Fernandes I.P.,Alves M.J.,Barros L.,González-Paramás A.M.,Ferreira I.C.F.R.,Barreiro M.F.
Mushroom-based cosmeceutical ingredients: Microencapsulation and in vitro release profile
Industrial Crops and Products, 124, 44-52, 2018

76
Almeida H.H.S.,Barros L.,Barreira J.C.M.,Calhelha R.C.,Heleno S.A.,Sayer C.,Miranda C.G.,Leimann F.V.,Barreiro M.F.,Ferreira I.C.F.R.
Bioactive evaluation and application of different formulations of the natural colorant curcumin (E100) in a hydrophilic matrix (yogurt)
Food Chemistry, 261, 224-232, 2018

77
Halla N.,Heleno S.A.,Costa P.,Fernandes I.P.,Calhelha R.C.,Boucherit K.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Chemical profile and bioactive properties of the essential oil isolated from Ammodaucus leucotrichus fruits growing in Sahara and its evaluation as a cosmeceutical ingredient
Industrial Crops and Products, 119, 249-254, 2018

78
Francisco C.R.L.,Heleno S.A.,Fernandes I.P.M.,Barreira J.C.M.,Calhelha R.C.,Barros L.,Gonçalves O.H.,Ferreira I.C.F.R.,Barreiro M.F.
Functionalization of yogurts with Agaricus bisporus extracts encapsulated in spray-dried maltodextrin crosslinked with citric acid
Food Chemistry, 245, 845-853, 2018

79
Villavicencio A.L.C.H.,Heleno S.A.,Calhelha R.C.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
The influence of electron beam radiation in the nutritional value, chemical composition and bioactivities of edible flowers of Bauhinia variegata L. var. candida alba Buch.-Ham from Brazil
Food Chemistry, 241, 163-170, 2018

80
Rached W.,Zeghada F.Z.,Bennaceur M.,Barros L.,Calhelha R.C.,Heleno S.,Alves M.J.,Carvalho A.M.,Marouf A.,Ferreira I.C.F.R.
Phytochemical analysis and assessment of antioxidant, antimicrobial, anti-inflammatory and cytotoxic properties of Tetraclinis articulata (Vahl) Masters leaves
Industrial Crops and Products, 112, 460-466, 2018

81
Halla N.,Fernandes I.P.,Heleno S.A.,Costa P.,Boucherit-Otmani Z.,Boucherit K.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Cosmetics preservation: A review on present strategies
Molecules, 23, , 2018

82
Oludemi T.,Barros L.,Prieto M.A.,Heleno S.A.,Barreiro M.F.,Ferreira I.C.F.R.
Extraction of triterpenoids and phenolic compounds from: Ganoderma lucidum: Optimization study using the response surface methodology
Food and Function, 9, 209-226, 2018

83
Ziani B.E.C.,Barros L.,Boumehira A.Z.,Bachari K.,Heleno S.A.,Alves M.J.,Ferreira I.C.F.R.
Profiling polyphenol composition by HPLC-DAD-ESI/MSn and the antibacterial activity of infusion preparations obtained from four medicinal plants
Food and Function, 9, 149-159, 2018

84
Taofiq O.,Heleno S.A.,Calhelha R.C.,Alves M.J.,Barros L.,González-Paramás A.M.,Barreiro M.F.,Ferreira I.C.F.R.
The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits
Food and Chemical Toxicology, 108, 139-147, 2017

85
Rached W.,Bennaceur M.,Barros L.,Calhelha R.C.,Heleno S.,Alves M.J.,Carvalho A.M.,Marouf A.,Ferreira I.C.F.R.
Detailed phytochemical characterization and bioactive properties of: Myrtus nivelii Batt & Trab
Food and Function, 8, 3111-3119, 2017

86
Ferreira I.C.F.R.,Fernandes Â.,Heleno S.A.
Chemical, nutritional, and bioactive potential of mushrooms
Edible and Medicinal Mushrooms: Technology and Applications, 455-501, 2017

87
Svobodova B.,Barros L.,Sopik T.,Calhelha R.C.,Heleno S.,Alves M.J.,Walcott S.,Kuban V.,Ferreira I.C.F.R.
Non-edible parts of Solanum stramoniifolium Jacq.-a new potent source of bioactive extracts rich in phenolic compounds for functional foods
Food and Function, 8, 2013-2021, 2017

88
Svobodova B.,Barros L.,Calhelha R.C.,Heleno S.,Alves M.J.,Walcott S.,Bittova M.,Kuban V.,Ferreira I.C.F.R.
Bioactive properties and phenolic profile of Momordica charantia L. medicinal plant growing wild in Trinidad and Tobago
Industrial Crops and Products, 95, 365-373, 2017

89
Heleno S.A.,Rudke A.R.,Calhelha R.C.,Carocho M.,Barros L.,Gonçalves O.H.,Barreiro M.F.,Ferreira I.C.F.R.
Development of dairy beverages functionalized with pure ergosterol and mycosterol extracts: An alternative to phytosterol-based beverages
Food and Function, 8, 103-110, 2017

90
Antonio A.L.,Pereira E.,Pinela J.,Heleno S.,Pereira C.,Ferreira I.C.F.R.
Determination of antioxidant compounds in foodstuff
Food Safety: Innovative Analytical Tools for Safety Assessment, 179-220, 2016

91
Taofiq O.,Heleno S.A.,Calhelha R.C.,Alves M.J.,Barros L.,Barreiro M.F.,González-Paramás A.M.,Ferreira I.C.F.R.
Development of Mushroom-Based cosmeceutical formulations with Anti-Inflammatory, Anti-Tyrosinase, antioxidant, and antibacterial properties
Molecules, 21, , 2016

92
Heleno S.A.,Prieto M.A.,Barros L.,Rodrigues A.,Barreiro M.F.,Ferreira I.C.F.R.
Optimization of microwave-assisted extraction of ergosterol from Agaricus bisporus L. by-products using response surface methodology
Food and Bioproducts Processing, 100, 25-35, 2016

93
Heleno S.A.,Diz P.,Prieto M.A.,Barros L.,Rodrigues A.,Barreiro M.F.,Ferreira I.C.F.R.
Optimization of ultrasound-assisted extraction to obtain mycosterols from Agaricus bisporus L. by response surface methodology and comparison with conventional Soxhlet extraction
Food Chemistry, 197, 1054-1063, 2016

94
Taofiq O.,Calhelha R.C.,Heleno S.,Barros L.,Martins A.,Santos-Buelga C.,Queiroz M.J.R.P.,Ferreira I.C.F.R.
The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: Screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives
Food Research International, 76, 821-827, 2015

95
Heleno S.A.,Barros L.,Martins A.,Morales P.,Fernández-Ruiz V.,Glamoclija J.,Sokovic M.,Ferreira I.C.F.R.
Nutritional value, bioactive compounds, antimicrobial activity and bioaccessibility studies with wild edible mushrooms
LWT, 63, 799-806, 2015

96
Heleno S.A.,Ferreira R.C.,Antonio A.L.,Queiroz M.J.R.P.,Barros L.,Ferreira I.C.F.R.
Nutritional value, bioactive compounds and antioxidant properties of three edible mushrooms from Poland
Food Bioscience, 11, 48-55, 2015

97
Heleno S.A.,Barros L.,Martins A.,Queiroz M.J.R.P.,Morales P.,Fernández-Ruiz V.,Ferreira I.C.F.R.
Chemical composition, antioxidant activity and bioaccessibility studies in phenolic extracts of two Hericium wild edible species
LWT, 63, 475-481, 2015

98
Ferreira I.C.F.R.,Heleno S.A.,Reis F.S.,Stojkovic D.,Queiroz M.J.R.P.,Vasconcelos M.H.,Sokovic M.
Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
Phytochemistry, 114, 38-55, 2015

99
Heleno S.A.,Martins A.,Queiroz M.J.R.P.,Ferreira I.C.F.R.
Bioactivity of phenolic acids: Metabolites versus parent compounds: A review
Food Chemistry, 173, 501-513, 2015

100
Heleno S.A.,Ferreira I.C.F.R.,Ćirić A.,Glamočlija J.,Martins A.,Queiroz M.J.R.P.,Soković M.
Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents
Food and Function, 5, 2521-2528, 2014

101
Heleno S.A.,Ferreira I.C.F.R.,Calhelha R.C.,Esteves A.P.,Martins A.,Queiroz M.J.R.P.
Cytotoxicity of Coprinopsis atramentaria extract, organic acids and their synthesized methylated and glucuronate derivatives
Food Research International, 55, 170-175, 2014

102
Heleno S.A.,Ferreira I.C.F.R.,Esteves A.P.,Ćirić A.,Glamočlija J.,Martins A.,Soković M.,Queiroz M.J.R.P.
Antimicrobial and demelanizing activity of Ganoderma lucidum extract, p-hydroxybenzoic and cinnamic acids and their synthetic acetylated glucuronide methyl esters
Food and Chemical Toxicology, 58, 95-100, 2013

103
Heleno S.A.,Stojković D.,Barros L.,Glamočlija J.,Soković M.,Martins A.,Queiroz M.J.R.P.,Ferreira I.C.F.R.
A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia
Food Research International, 51, 236-243, 2013

104
Heleno S.A.,Barros L.,Martins A.,Queiroz M.J.R.P.,Santos-Buelga C.,Ferreira I.C.F.R.
Phenolic, polysaccharidic, and lipidic fractions of mushrooms from northeastern portugal: Chemical compounds with antioxidant properties
Journal of Agricultural and Food Chemistry, 60, 4634-4640, 2012

105
Heleno S.A.,Barros L.,Martins A.,Queiroz M.J.R.P.,Santos-Buelga C.,Ferreira I.C.F.R.
Fruiting body, spores and in vitro produced mycelium of Ganoderma lucidum from Northeast Portugal: A comparative study of the antioxidant potential of phenolic and polysaccharidic extracts
Food Research International, 46, 135-140, 2012

106
Reis F.S.,Heleno S.A.,Barros L.,Sousa M.J.,Martins A.,Santos-Buelga C.,Ferreira I.C.F.R.
Toward the Antioxidant and Chemical Characterization of Mycorrhizal Mushrooms from Northeast Portugal
Journal of Food Science, 76, , 2011

107
Grangeia C.,Heleno S.A.,Barros L.,Martins A.,Ferreira I.C.F.R.
Effects of trophism on nutritional and nutraceutical potential of wild edible mushrooms
Food Research International, 44, 1029-1035, 2011

108
Heleno S.A.,Barros L.,Sousa M.J.,Martins A.,Santos-Buelga C.,Ferreira I.C.F.R.
Targeted metabolites analysis in wild Boletus species
LWT, 44, 1343-1348, 2011

109
Vaz J.A.,Heleno S.A.,Martins A.,Almeida G.M.,Vasconcelos M.H.,Ferreira I.C.F.R.
Wild mushrooms Clitocybe alexandri and Lepista inversa: In vitro antioxidant activity and growth inhibition of human tumour cell lines
Food and Chemical Toxicology, 48, 2881-2884, 2010

110
Heleno S.A.,Barros L.,Sousa M.J.,Martins A.,Ferreira I.C.F.R.
Tocopherols composition of Portuguese wild mushrooms with antioxidant capacity
Food Chemistry, 119, 1443-1450, 2010

111
Barros L.,Heleno S.A.,Carvalho A.M.,Ferreira I.C.F.R.
Lamiaceae often used in Portuguese folk medicine as a source of powerful antioxidants: Vitamins and phenolics
LWT, 43, 544-550, 2010

112
Heleno S.A.,Barros L.,Sousa M.J.,Martins A.,Ferreira I.C.F.R.
Study and characterization of selected nutrients in wild mushrooms from Portugal by gas chromatography and high performance liquid chromatography
Microchemical Journal, 93, 195-199, 2009

113
Barros L.,Heleno S.A.,Carvalho A.M.,Ferreira I.C.F.R.
Systematic evaluation of the antioxidant potential of different parts of Foeniculum vulgare Mill. from Portugal
Food and Chemical Toxicology, 47, 2458-2464, 2009

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