MOUNTAIN
RESEARCH
CENTER

Polytechnic Institute
of Bragança

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CIMO

CIMO - Mountain Research Center. See video HERE

FROM NATURE TO PRODUCTS, TOWARDS SUSTAINABILITY.

Ana Filipa Mandim Pires

Group: Sustainable Processes and Products
E-mail: filipamandim@ipb.pt
ORCID: 0000-0002-6494-2326
Scopus Author ID: 57205489742

Career

  • Since 2024: Post-doc Fellow, Polytechnic Institute of Bragança, Portugal
  • 2020 - 2024: PhD Research Fellow (SFRH/BD/1446614/2019) financed by the Foundation for Science and Technology, Mountain Research Centre, Polytechnic Institute of Bragança, Portugal
  • 2020 2018: Research Fellow, Polytechnic Institute of Bragança, Portugal

Roles

  • Since 2023: Review editor in indexed journal Food Chemistry, Frontiers in Nutrition.

Qualifications

  • 2024 - PhD. in Pharmacy and Health, Salamanca University, Spain
  • 2018 - MSc. in Pharmacy and Chemistry of Natural Products, Polytechnic Institute of Bragança, Portugal and Salamanca University, Spain
  • 2016 - Graduation in Medicinal Chemistry, University Trás-os-Montes and Alto Douro, Portugal

Awards and Honors

  • 2023 - Best Oral Presentation Award at 8th Portuguese Young Chemists Meeting, Vila Real, Portugal
  • 2023 - Elsevier's Outstanding Reviewer recognition
  • 2022 - Elsevier's Outstanding Reviewer recognition
  • 2021 - Elsevier's Outstanding Reviewer recognition

Interests

  • Extraction of bioactive compounds from natural matrices: evaluation of their effects on human health
  • Development of innovative food products with functional properties
  • Study the natural extracts' effects on cell cultures to improve the final product’s nutritional and functional value

Projects:

TRANSCOLAB PLUS - Laboratorio Colaborativo Transfronterizo para la transicion verde del sector Agroalimentario y Agroindustrial
Funding body: POCTEP 2021-2027 - Programa de Cooperação Transfronteiriça Portugal – Espanha
Reference: 0112_TRANSCOLAB_PLUS_2_P
Principal Investigator:Lillian Bouçada de Barros
Start: 2023-10-01
End: 2026-12-31
NEWPOWER - Valorización integral de residuos agroforestales: Nuevas biorrefinerías multiproducto escalables
Funding body: Interreg Sudoe
Reference:
Principal Investigator:Lillian Bouçada de Barros
Start: 2024-01-01
End: 2026-12-31
TRANSCoLAB - Laboratorio Colaborativo Transfronterizo para la sostenibilidad y innovación del sector Agroalimentario y Agroindustrial
Funding body: POCTEP 2014-2020 - Programa de Cooperação Transfronteiriça Portugal – Espanha
Reference: 0612_TRANS_CO_LAB_2_P
Principal Investigator:Lillian Bouçada de Barros
Start: 2018-01-01
End: 2022-04-05
IBERPHENOL - Red cooperativa de investigación en el ámbito de polifenoles y sus aplicaciones industriales
Funding body: POCTEP 2014-2020 - Programa de Cooperação Transfronteiriça Portugal – Espanha
Reference: 0377_IBERPHENOL_6_E
Principal Investigator:Lillian Bouçada de Barros
Start: 2015-10-01
End: 2020-12-31
Halófitas Vermelhas - Halófitas vermelhas como nova fonte de biomoléculas com aplicação na indústria alimentar, nutracêutica e medicina
Funding body: Programa bilateral Portugal/Tunísia
Reference:
Principal Investigator:João Carlos Martins Barreira
Start: 2019-01-01
End: 2020-12-31

Total results: 55
1
Mateus C.,Alonso-Esteban J.I.,Finimundy T.C.,Mandim F.,Oliveira I.,Babo P.,Canadas R.F.,Ferreira I.C.F.R.,Barros L.
Exploring acorn shells: Phenolic composition and bioactive potential for sustainable valorization
Industrial Crops and Products, 226, , 2025

2
Oliveira J.,Benvenutti L.,Albuquerque B.R.,Finimundy T.C.,Mandim F.,Pires T.C.S.P.,Pereira C.,Corrêa R.C.G.,Barros L.,Zielinski A.A.F.
Green extraction of anthocyanin from red cabbage waste using acid whey as a promising bio-based solvent
Innovative Food Science and Emerging Technologies, 100, , 2025

3
Añibarro-Ortega M.,Dias M.I.,Petrović J.,Mandim F.,Núñez S.,Soković M.,López V.,Barros L.,Pinela J.
Nutrients, Phytochemicals, and In Vitro Biological Activities of Goldenberry (Physalis peruviana L.) Fruit and Calyx
Plants, 14, , 2025

4
Pallarés N.,Berrada H.,Ferrer E.,Rached W.,Pinela J.,Mandim F.,Pires T.C.S.P.,Finimundy T.C.,Barba F.J.,Barros L.
Green and Innovative Extraction: Phenolic Profiles and Biological Activities of Underutilized Plant Extracts Using Pulsed Electric Fields and Maceration
Foods, 14, , 2025

5
Radhouane M.F.,da Silveira T.F.F.,Ribeiro J.,Rodrigues P.,Guimarães R.,Calhelha R.,Mandim F.,Charfi I.,Ferreira I.C.F.R.,Alves M.J.,Barros L.,Heleno S.A.
Development, characterization and stability of a novel sport drink based on thermal water, apple juice and hibiscus
Food Chemistry Advances, 5, , 2024

6
Santos Filipe M.,Kowalczyk T.,Kukula-Koch W.,Wieczfinska J.,Bangay G.,Diaz-Lanza A.M.,Cardoso R.V.C.,Mandim F.,I. Falcão S.,Vilas-Boas M.,Śliwiński T.,Sitarek P.,Ríjo P.
Evaluating the quality, physicochemical properties, and biological activities of Centauri® honey from Turkey
Food Bioscience, 62, , 2024

7
Mandim F.,Petropoulos S.A.,Pinto C.A.,Heleno S.A.,Rodrigues P.,Dias M.I.,Saraiva J.A.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.,Pinela J.
Novel cold and thermally pasteurized cardoon-enriched functional smoothie formulations: A zero-waste manufacturing approach
Food Chemistry, 456, , 2024

8
Șen A.U.,Almeida D.,da Silveira T.F.F.,Pires T.S.P.,Añibarro-Ortega M.,Mandim F.,Barros L.,Ferreira I.C.F.R.,Pereira H.,Fernandes Â.
Bioactivities of Waste Cork and Phloem Fractions of Quercus cerris Bark
Processes, 12, , 2024

9
Correa V.G.,Garcia-Manieri J.A.A.,Dias M.I.,Pereira C.,Mandim F.,Barros L.,Ferreira I.C.F.R.,Peralta R.M.,Bracht A.
Gastrointestinal digestion of yerba mate, rosemary and green tea extracts and their subsequent colonic fermentation by human, pig or rat inocula
Food Research International, 194, , 2024

10
Liava V.,Fernandes Â.,Reis F.,Finimundy T.,Mandim F.,Pinela J.,Stojković D.,Ferreira I.C.F.R.,Barros L.,Petropoulos S.A.
How Does Domestic Cooking Affect the Biochemical Properties of Wild Edible Greens of the Asteraceae Family?
Foods, 13, , 2024

11
Mandim F.,Carocho M.,Petropoulos S.A.,Santos-Buelga C.,Barros L.
Effect of Different Seasons and Development Stages on the Chemical Composition and Bioactive Potential of Cardoon
Foods, 13, , 2024

12
Sen U.,Almeida D.,da Silveira T.F.F.,Pires T.S.P.,Añibarro-Ortega M.,Mandim F.,Barros L.,Ferreira I.C.F.R.,Pereira H.,Fernandes Â.
Exploring the Bioactive Properties of Hydroethanolic Cork Extracts of Quercus cerris and Quercus suber
Processes, 12, , 2024

13
Añibarro-Ortega M.,López V.,Núñez S.,Petrović J.,Mandim F.,Barros L.,Soković M.,Ferreira I.C.F.R.,Dias M.I.,Pinela J.
Phenolic composition and in vitro bioactive and enzyme inhibitory properties of bell pepper (Capsicum annuum L.) plant extracts
Industrial Crops and Products, 214, , 2024

14
Sena J.d.S.,Rodrigues S.A.,Sakumoto K.,Inumaro R.S.,González-Maldonado P.,Mendez-Scolari E.,Piau R.,Gonçalves D.D.,Mandim F.,Vaz J.,Gonçalves J.E.,Sotelo P.H.,Valle J.S.d.,Gazim Z.C.
Antioxidant Activity, Antiproliferative Activity, Antiviral Activity, NO Production Inhibition, and Chemical Composition of Essential Oils and Crude Extracts of Leaves, Flower Buds, and Stems of Tetradenia riparia
Pharmaceuticals, 17, , 2024

15
Filipe M.S.,Domínguez-Martín E.M.,Pires T.C.S.P.,Finimundy T.C.,Melgar B.,Mandim F.,Isca V.M.S.,Pereira R.,Teixidó-Trujillo S.,Capote N.A.,Nikolić M.,Filipović N.,Díaz-Lanza A.M.,Figueiredo A.C.,Barros L.,Rijo P.
Biological Activity of 6,7-Dehydroxyroyleanone and Derivatives Obtained from Plectranthus aliciae (Codd) A.J.Paton
ACS Omega, 9, 18113-18118, 2024

16
Mandim F.,Pinela J.,Marcelino S.,Dias M.I.,Barracosa P.,Ivanov M.,Soković M.,Santos-Buelga C.,Barros L.
Insights into the phenolic composition and in vitro bioactivity of cardoon capitulum: A nutraceutical-oriented valorization study
Food Chemistry, 435, , 2024

17
Salvati D.,Paschoalinotto B.H.,Mandim F.,Ferreira I.C.F.R.,Steinmacher N.C.,Pereira C.,Dias M.I.
Exploring the Impacts of Sorghum (Sorghum bicolor L. Moench) Germination on the Flour’s Nutritional, Chemical, Bioactive, and Technological Properties
Foods, 13, , 2024

18
de Medeiros J.P.,Rodrigues S.A.,Sakumoto K.,Ruiz S.P.,Faria M.G.I.,Gonçalves J.E.,Piau Junior R.,Glamočlija J.,Soković M.,Gonçalves D.D.,Mandim F.,Barros L.,Gazim Z.C.
Bioactives of the essential oil from the leaves of Eugenia pyriformis Cambess (Myrtaceae) on the effects of tobacco
Frontiers in Pharmacology, 15, , 2024

19
Rahal I.L.,Dias A.B.,Canonico Silva G.C.,Vieira de Araújo Bento M.C.,Ayob Casalvara R.F.,Gonçalves J.E.,Colauto N.B.,Linde G.A.,Mandim F.,Vaz J.,Barros L.,do Valle J.S.,Gazim Z.C.
Pachira aquatica: biological activity and chemical composition of leaves, flowers, and seeds
Natural Product Research, , 2024

20
Ames-Sibin A.P.,Chagas A.C.,Ferreira S.B.S.,Mandim F.,Finimundy T.C.,Calhelha R.C.,Peralta R.M.,Sá-Nakanishi A.B.,Bracht L.,Bruschi M.L.,Bracht A.,Barros L.,Comar J.F.
Characterization and bioactivity of copaiba essential oil carried in a self-nanoemulsifying drug delivery system
Journal of Drug Delivery Science and Technology, 91, , 2024

21
Santos Filho J.R.d.,Santos É.d.S.,Mandim F.,Molina A.K.,Barros L.,Correia Gonçalves R.A.,Braz de Oliveira A.J.,Ferreira I.C.P.
Evaluation of antitumoral and antioxidant activities of the hydroalcoholic extract and fractions obtained from the fruit pericarp of Sapindus saponaria L.
Natural Product Research, 38, 1002-1006, 2024

22
Albuquerque B.R.,Pinela J.,Pereira C.,Mandim F.,Heleno S.,Oliveira M.B.P.P.,Barros L.
Recovery of anthocyanins from Eugenia spp. fruit peels: a comparison between heat- and ultrasound-assisted extraction
Sustainable Food Technology, 2, 189-201, 2023

23
Mandim F.,Santos-Buelga C.,C.F.R. Ferreira I.,Petropoulos S.A.,Barros L.
The wide spectrum of industrial applications for cultivated cardoon (Cynara cardunculus L. var. Altilis DC.): A review
Food Chemistry, 423, , 2023

24
Martins de Deus B.,Fernandes C.,Molina A.K.,Xavier V.,Pires T.C.S.P.,Mandim F.,Heleno S.A.,Finimundy T.C.,Barros L.
Chemical Characterization, Bioactivity and Toxicity of European Flora Plant Extracts in Search for Potential Natural Origin Preservatives
Plants, 12, , 2023

25
Fernandes Â.,Polyzos N.,Mandim F.,Pereira C.,Petrović J.,Soković M.,Petropoulos S.A.
Combined Effect of Biostimulants and Mineral Fertilizers on Crop Performance and Fruit Quality of Watermelon Plants
Horticulturae, 9, , 2023

26
Silva G.C.C.,Machado M.d.A.,Sakumoto K.,Inumaro R.S.,Gonçalves J.E.,Mandim F.,Vaz J.,do Valle J.S.,Faria M.G.I.,Ruiz S.P.,Piau Junior R.,Gonçalves D.D.,Gazim Z.C.
Cellular Antioxidant, Anti-Inflammatory, and Antiproliferative Activities from the Flowers, Leaves and Fruits of Gallesia integrifolia Spreng Harms
Molecules, 28, , 2023

27
Albuquerque B.R.,Finimundy T.C.,Pinela J.,Pires T.C.S.P.,Mandim F.,Vaz J.,Corrêa R.C.G.,Oliveira M.B.P.P.,Barros L.
Brazilian berry waste as a source of bioactive compounds: grumixama (Eugenia brasiliensis Lam.) as a case study
Food and Function, 14, 3994-4005, 2023

28
Marcelino S.,Mandim F.,Taofiq O.,Pires T.C.S.P.,Finimundy T.C.,Prieto M.A.,Barros L.
Valorization of Punica granatum L. Leaves Extracts as a Source of Bioactive Molecules
Pharmaceuticals, 16, , 2023

29
Pereira E.,Fernandes F.A.,Mandim F.,Ayuso M.,Ferreira I.C.F.R.,Caleja C.,Barros L.
Non-alkaloid nitrogen containing compounds
Natural Secondary Metabolites: From Nature, Through Science, to Industry, 331-362, 2023

30
Essoh A.P.,Cassiano G.C.,Mandim F.,Barros L.,Gomes I.,Medeiros M.M.,Moura M.,Cravo P.V.L.,Romeiras M.M.
Antimalarial and Cytotoxic Activity of Native Plants Used in Cabo Verde Traditional Medicine
Plants, 12, , 2023

31
da Silva T.B.V.,Dias M.I.,Pereira C.,Mandim F.,Ivanov M.,Soković M.,Ferreira I.C.F.R.,Barros L.,Seixas F.A.V.,Bracht A.,Peralta R.M.
Purple tea: chemical characterization and evaluation as inhibitor of pancreatic lipase and fat digestion in mice
Food and Function, 14, 1761-1772, 2023

32
Pinela J.,Fuente B.d.l.,Rodrigues M.,Pires T.C.S.P.,Mandim F.,Almeida A.,Dias M.I.,Caleja C.,Barros L.
Upcycling Fish By-Products into Bioactive Fish Oil: The Suitability of Microwave-Assisted Extraction
Biomolecules, 13, , 2023

33
Cavichi L.V.,Liberal Â.,Dias M.I.,Mandim F.,Pinela J.,Kostić M.,Soković M.,Kalschne D.L.,Fernandes Â.,Canan C.,Barros L.,Amaral J.S.
Chemical Composition and Biological Activity of Commelina erecta: An Edible Wild Plant Consumed in Brazil
Foods, 12, , 2023

34
Zaier M.M.,Heleno S.A.,Mandim F.,Calhelha R.C.,Ferreira I.C.F.R.,Achour L.,Kacem A.,Dias M.I.,Barros L.
Effects of the seasonal variation in the phytochemical composition and bioactivities of the wild halophyte Suaeda fruticosa
Food Bioscience, 50, , 2022

35
Othman S.,Añibarro-Ortega M.,Dias M.I.,Ćirić A.,Mandim F.,Soković M.,Ferreira I.C.F.R.,Pinela J.,Barros L.
Valorization of quince peel into functional food ingredients: A path towards “zero waste” and sustainable food systems
Heliyon, 8, , 2022

36
da Silva Santos É.,Savam A.,Cabral M.R.P.,Castro J.C.,de Oliveira Collet S.A.,Mandim F.,Calhelha R.C.,Barros L.,da Silva Machado M.d.F.P.,de Oliveira A.J.B.,Gonçalves R.A.C.
Low-cost alternative for the bioproduction of bioactive phenolic compounds of callus cultures from Cereus hildmannianus (K.) Schum
Journal of Biotechnology, 356, 8-18, 2022

37
P. Essoh A.,Liberal Â.,Fernandes Â.,Dias M.I.,Pereira C.,Mandim F.,Moldão-Martins M.,Cravo P.,Duarte M.P.,Moura M.,Romeiras M.M.,Barros L.
Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
Pharmaceuticals, 15, , 2022

38
de la Fuente B.,Pinela J.,Mandim F.,Heleno S.A.,Ferreira I.C.F.R.,Barba F.J.,Berrada H.,Caleja C.,Barros L.
Nutritional and bioactive oils from salmon (Salmo salar) side streams obtained by Soxhlet and optimized microwave-assisted extraction
Food Chemistry, 386, , 2022

39
Mandim F.,Petropoulos S.A.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Effect of Harvesting Time on the Chemical Composition of Cynara cardunculus L. var. altilis Blades
Agronomy, 12, , 2022

40
Mandim F.,Petropoulos S.A.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Chemical composition of cardoon (Cynara cardunculus L. var. altilis) petioles as affected by plant growth stage
Food Research International, 156, , 2022

41
Mandim F.,Petropoulos S.A.,Pinela J.,Dias M.I.,Kostic M.,Soković M.,Ferreira I.C.F.R.,Santos-Buelga C.,Barros L.
Phenolic Composition and Antioxidant, Anti-Inflammatory, Cytotoxic, and Antimicrobial Activities of Cardoon Blades at Different Growth Stages
Biology, 11, , 2022

42
Besrour N.,Oludemi T.,Mandim F.,Pereira C.,Dias M.I.,Soković M.,Stojković D.,Ferreira O.,Ferreira I.C.F.R.,Barros L.
Article Valorization of Juglans regia Leaves as Cosmeceutical Ingredients: Bioactivity Evaluation and Final Formulation Development
Antioxidants, 11, , 2022

43
Kessler J.C.,Vieira V.A.,Martins I.M.,Manrique Y.A.,Afonso A.,Ferreira P.,Mandim F.,Ferreira I.C.F.R.,Barros L.,Rodrigues A.E.,Dias M.M.
Obtaining Aromatic Extracts from Portuguese Thymus mastichina L. by Hydrodistillation and Supercritical Fluid Extraction with CO2 as Potential Flavouring Additives for Food Applications
Molecules, 27, , 2022

44
Mandim F.,Petropoulos S.A.,Pinela J.,Dias M.I.,Giannoulis K.D.,Kostić M.,Soković M.,Queijo B.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Chemical composition and biological activity of cardoon (Cynara cardunculus L. var. altilis) seeds harvested at different maturity stages
Food Chemistry, 369, , 2022

45
Dutra T.V.,de Menezes J.L.,Mizuta A.G.,de Oliveira A.,Moreira T.F.M.,Barros L.,Mandim F.,Pereira C.,Gonçalves O.H.,Leimann F.V.,Mikcha J.M.G.,Machinski Junior M.,Abreu Filho B.A.d.
Use of nanoencapsulated curcumin against vegetative cells and spores of Alicyclobacillus spp. in industrialized orange juice
International Journal of Food Microbiology, 360, , 2021

46
Mandim F.,Petropoulos S.A.,Dias M.I.,Pinela J.,Kostić M.,Soković M.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Phenolic composition and biological properties of cynara cardunculus l. Var. altilis petioles: Influence of the maturity stage
Antioxidants, 10, , 2021

47
Cardoso R.V.C.,Fernandes Â.,Barreira J.C.M.,Abreu R.M.V.,Mandim F.,Gonzaléz-Paramás A.M.,Ferreira I.C.F.R.,Barros L.
A case study on surplus mushrooms production: Extraction and recovery of vitamin d2
Agriculture (Switzerland), 11, , 2021

48
Mandim F.,Petropoulos S.A.,Dias M.I.,Pinela J.,Kostic M.,Soković M.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Seasonal variation in bioactive properties and phenolic composition of cardoon (Cynara cardunculus var. altilis) bracts
Food Chemistry, 336, , 2021

49
Mandim F.,Petropoulos S.A.,Giannoulis K.D.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Chemical composition of cynara cardunculus l. Var. altilis bracts cultivated in central greece: the impact of harvesting time
Agronomy, 10, , 2020

50
Mandim F.,Dias M.I.,Pinela J.,Barracosa P.,Ivanov M.,Stojković D.,Soković M.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
Chemical composition and in vitro biological activities of cardoon (Cynara cardunculus L. var. altilis DC.) seeds as influenced by viability: Chemical prospection and bioactivity of cardoon seeds
Food Chemistry, 323, , 2020

51
Mandim F.,Petropoulos S.A.,Fernandes Â.,Santos-Buelga C.,Ferreira I.C.F.R.,Barros L.
Chemical composition of cynara cardunculus L. var. altilis heads: The impact of harvesting time
Agronomy, 10, , 2020

52
Mandim F.,Petropoulos S.A.,Giannoulis K.D.,Dias M.I.,Fernandes Â.,Pinela J.,Kostic M.,Soković M.,Barros L.,Santos-Buelga C.,Ferreira I.C.F.R.
Seasonal variation of bioactive properties and phenolic composition of Cynara cardunculus var. altilis
Food Research International, 134, , 2020

53
Mandim F.,Barros L.,Heleno S.A.,Pires T.C.S.P.,Dias M.I.,Alves M.J.,Santos P.F.,Ferreira I.C.F.R.
Phenolic profile and effects of acetone fractions obtained from the inflorescences of: Calluna vulgaris (L.) Hull on vaginal pathogenic and non-pathogenic bacteria
Food and Function, 10, 2399-2407, 2019

54
Mandim F.,Graça V.C.,Calhelha R.C.,Machado I.L.F.,Ferreira L.F.V.,Ferreira I.C.F.R.,Santos P.F.
Synthesis, photochemical and in vitro cytotoxic evaluation of new iodinated aminosquaraines as potential sensitizers for photodynamic therapy
Molecules, 24, , 2019

55
Mandim F.,Barros L.,Calhelha R.C.,Abreu R.M.V.,Pinela J.,Alves M.J.,Heleno S.,Santos P.F.,Ferreira I.C.F.R.
Calluna vulgaris (L.) Hull: Chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota
Food and Function, 10, 78-89, 2019

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