MOUNTAIN
RESEARCH
CENTER

Polytechnic Institute
of Bragança

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CIMO

CIMO - Mountain Research Center. See video HERE

FROM NATURE TO PRODUCTS, TOWARDS SUSTAINABILITY.

Maria Olga Ferreira

Group: Sustainable Processes and Products
Phone: 273303087
E-mail: oferreira@ipb.pt
ORCID: 0000-0001-8414-3479
Scopus Author ID: 7004914794

Career

  • Since 2010: Auxiliary Professor at the School of Technology and Management of the Polytechnic Institute of Bragança (ESTiG-IPB), Portugal
  • 2005 - 2018: Member of the research staff of Laboratory of Separation and Reaction Engineering at the Faculty of Engineering of the University of Porto (LSRE-FEUP), Portugal
  • 2004 - 2010: Assistant Professor at the School of Technology and Management of the Polytechnic Institute of Bragança (ESTiG-IPB), Portugal

Qualifications

  • 2003 - PhD. in the area of "Thermodynamic modelling of association effects by group-contribution: application to natural products", Faculty of Engineering of the University of Porto (FEUP), Portugal
  • 1998 - Graduation in Chemical Engineering, Faculty of Engineering of the University of Porto (FEUP), Portugal

Interests

  • Thermodynamic modelling of association effects by group contribution: application to natural products
  • The study of solubility and related thermodynamic properties of amino acids and peptides
  • Application of natural deep eutectic solvents for the extraction of bioactive compounds from plant material
  • Characterization of the physical properties of nonconventional solvents

Projects:

BIOSHOES4ALL - Inovação e Capacitação da Fileira do Calçado para a Bieconomia Sustentável
Funding body: PRR 2020 - Plano de Recuperação e Resiliência
Reference: PRR - 000011
Principal Investigator:Maria Filomena Filipe Barreiro
Start: 2021-10-01
End: 2025-12-31
- STEM AND EQUALITY, DIVERSITY AND INCLUSION: an open dialogue for research enhancement in Portugal – STEP
Funding body: Horizon 2020
Reference: 01078933 — STEP — HORIZON-WIDERA-2021-ACCESS-03
Start: 2023-01-01
End: 2025-12-31
- Assessment of Reliability and Uncertainty of Solubility Data
Funding body: IUPAC - International Union of Pure and Applied Chemistry (Suíça)
Reference: 2022-002-2-500
Principal Investigator:Simão Pedro de Almeida Pinho
Start: 2022-05-10
End: 2024-06-09
Acorn4Med - Enhancement of acorn forest waste for application in biomedicine
Funding body: Promove LA CAIXA
Reference: PV20-00038
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-04-01
End: 2024-03-31
OliveBIOextract - Aproveitamento sustentável do bagaço de azeitona numa cadeia de valorização integrada utilizando processos inovadores
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-0247-FEDER-049865
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-02-01
End: 2023-06-30
Bio4drinks - Obtenção de Ingredientes Naturais Multifuncionais para a Indústria de Bebidas
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-0247-FEDER-113508
Principal Investigator:Sandrina Alves Heleno
Start: 2021-09-01
End: 2023-06-30
INTEGRAVALOR - Estratégia integrada de valorização de subprodutos agroalimentares
Funding body: PORTUGAL 2020 - COMPETE 2020 - Programa Operacional Competitividade e Internacionalização
Reference: POCI-01-0247-FEDER-072241
Principal Investigator:Lillian Bouçada de Barros
Start: 2021-01-01
End: 2023-06-30
AllNat - Using natural deep eutectic solvents for the extraction of bioactive compounds from plant material
Funding body: PORTUGAL 2020 - COMPETE 2020 - Programa Operacional Competitividade e Internacionalização
Reference: POCI-01-0145-FEDER-030463
Principal Investigator:Maria Olga de Amorim e Sá Ferreira
Start: 2018-06-01
End: 2022-05-31
PlantCovid - Aplicações de extratos de plantas com ação dirigida ao SARS-CoV-2
Funding body: NORTE 2020 - Programa Operacional Regional do Norte
Reference: NORTE-01-02B/-FEDER-054870
Principal Investigator:Lillian Bouçada de Barros
Start: 2020-07-14
End: 2021-12-31
- Decyl Acetate Synthesis by Enzymatic Catalysis in Supercritical Media
Funding body: POCTI - Programa operacional Ciência, Tecnologia e Inovação
Reference: POCTI/QUE/56732/2004
Start: 2004-01-01
End: 2007-12-31

Total results: 66
1
Lima L.,Pereira A.I.,Vaz C.B.,Ferreira O.,Dias M.I.,Heleno S.A.,Calhelha R.C.,Barros L.,Carocho M.
Optimization of heat and ultrasound-assisted extraction of Eucalyptus globulus leaves reveals strong antioxidant and antimicrobial properties
Food Chemistry, 479, , 2025

2
Cordova I.W.,Oludemi T.,Vieira V.,Pires T.C.S.P.,Pinho S.P.,Barros L.,Ferreira O.
Extraction of phenolic compounds from Juglans regia L. leaves using aqueous solutions of eutectic solvents
Separation and Purification Technology, 354, , 2025

3
Vilas-Boas S.M.,Coutinho J.A.P.,Pinho S.P.,Ferreira O.
Solvent screening for the purification of monoterpenoids by countercurrent and centrifugal partition chromatography
Journal of Chemical Technology and Biotechnology, 100, 166-175, 2025

4
Ferreira O.,Silva L.P.,Almeida H.H.S.,Benfica J.,Abranches D.O.,Pinho S.P.,Coutinho J.A.P.
What is better to enhance the solubility of hydrophobic compounds in aqueous solutions: eutectic solvents or ionic liquids?
RSC Sustainability, 2, 4052-4060, 2024

5
Teixeira G.,Brandão P.,Lobo Ferreira A.I.M.C.,Abranches D.O.,Santos L.M.N.B.F.,Ferreira O.,Coutinho J.A.P.
Designing type V deep eutectic solvents with antimalarial pharmaceutical ingredients
European Journal of Pharmaceutics and Biopharmaceutics, 203, , 2024

6
de Rezende S.C.,Ferreira O.,Santamaria-Echart A.,Dias M.M.,Barreiro M.F.
Evaluating the potential of natural polymers for water-dispersible curcumin-based solid dispersion colourant systems for food applications
Journal of Food Engineering, 371, , 2024

7
Cordova I.W.,Teixeira G.,Ribeiro-Claro P.J.A.,Abranches D.O.,Pinho S.P.,Ferreira O.,Coutinho J.A.P.
Using Molecular Conformers in COSMO-RS to Predict Drug Solubility in Mixed Solvents
Industrial and Engineering Chemistry Research, 63, 9565-9575, 2024

8
9
Aliyeva M.,Brandão P.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Solubilities of Amino Acids in the Presence of Chaotropic Anions
Journal of Solution Chemistry, 53, 527-537, 2024

10
Vilas-Boas S.M.,Batista F.R.M.,Dias R.M.,Coutinho J.A.P.,Ferreira O.,da Costa M.C.,Pinho S.P.
Deterpenation of citrus essential oil via extractive distillation using imidazolium-based ionic liquids as entrainers
Journal of the Taiwan Institute of Chemical Engineers, 156, , 2024

11
Teixeira G.,Abranches D.O.,Ferreira O.,Coutinho J.A.P.
Estimating the Melting Temperatures of Type V Deep Eutectic Solvents
Industrial and Engineering Chemistry Research, 62, 14638-14647, 2023

12
Vilas-Boas S.M.,Coelho A.Z.,Martins M.A.R.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Evaluation of Ionic Liquids for the Sustainable Fractionation of Essential Oils
Industrial and Engineering Chemistry Research, 62, 6749-6758, 2023

13
Vilas-Boas S.M.,do Nascimento D.C.,Dias R.M.,Rozo G.H.,Barbosa Neto A.M.,Ferreira O.,Pinho S.P.,da Costa M.C.
Flash point of binary and ternary monoterpene mixtures: Experimental and modeling
Process Safety and Environmental Protection, 172, 1048-1057, 2023

14
Vilas-Boas S.M.,Cordova I.W.,Abranches D.O.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Modeling the Solubility of Monoterpenoids with Hybrid and Predictive Thermodynamic Tools
Industrial and Engineering Chemistry Research, 62, 5326-5335, 2023

15
Zambom A.,Vilas-Boas S.M.,Silva L.P.,Martins M.A.R.,Ferreira O.,Pinho S.P.
The Role of the Anion in Imidazolium-Based Ionic Liquids for Fuel and Terpenes Processing
Molecules, 28, , 2023

16
Aliyeva M.,Brandão P.,Gomes J.R.B.,Coutinho J.A.P.,Held C.,Ferreira O.,Pinho S.P.
Salt effects on the solubility of aromatic and dicarboxylic amino acids in water
Journal of Chemical Thermodynamics, 177, , 2023

17
Lima J.,Brito T.,Ferreira O.,Afonso M.J.,Pinto V.H.,Carvalho J.A.,Costa P.
A Data logger for educational purposes of a laboratory chemical reactor: an IoT approach
International Conference on Electrical, Computer, Communications and Mechatronics Engineering, ICECCME 2023, , 2023

18
Vilas-Boas S.M.,Martins M.A.R.,Tentor F.R.,Teixeira G.,Sgorlon J.G.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Imidazolium Chloride Ionic Liquid Mixtures as Separating Agents: Fuel Processing and Azeotrope Breaking
Energy and Fuels, 36, 8552-8561, 2022

19
Aliyeva M.,Brandão P.,Gomes J.R.B.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Solubilities of Amino Acids in Aqueous Solutions of Chloride or Nitrate Salts of Divalent (Mg2+or Ca2+) Cations
Journal of Chemical and Engineering Data, 67, 1565-1572, 2022

20
Lobo Ferreira A.I.M.C.,Vilas-Boas S.M.,Silva R.M.A.,Martins M.A.R.,Abranches D.O.,Soares-Santos P.C.R.,Almeida Paz F.A.,Ferreira O.,Pinho S.P.,Santos L.M.N.B.F.,Coutinho J.A.P.
Extensive characterization of choline chloride and its solid-liquid equilibrium with water
Physical Chemistry Chemical Physics, 24, 14886-14897, 2022

21
Teixeira G.,Abranches D.O.,Silva L.P.,Vilas-Boas S.M.,Pinho S.P.,Ferreira A.I.M.C.L.,Santos L.M.N.B.F.,Ferreira O.,Coutinho J.A.P.
Liquefying Flavonoids with Terpenoids through Deep Eutectic Solvent Formation
Molecules, 27, , 2022

22
Aliyeva M.,Brandão P.,Gomes J.R.B.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Electrolyte Effects on the Amino Acid Solubility in Water: Solubilities of Glycine, l -Leucine, l -Phenylalanine, and l -Aspartic Acid in Salt Solutions of (Na+, K+, NH4+)/(Cl-, NO3-)
Industrial and Engineering Chemistry Research, 61, 5620-5631, 2022

23
Besrour N.,Oludemi T.,Mandim F.,Pereira C.,Dias M.I.,Soković M.,Stojković D.,Ferreira O.,Ferreira I.C.F.R.,Barros L.
Article Valorization of Juglans regia Leaves as Cosmeceutical Ingredients: Bioactivity Evaluation and Final Formulation Development
Antioxidants, 11, , 2022

24
Vilas-Boas S.M.,Cordova I.W.,Kurnia K.A.,Almeida H.H.S.,Gaschi P.S.,Coutinho J.A.P.,Pinho S.P.,Ferreira O.
Comparison of two computational methods for solvent screening in countercurrent and centrifugal partition chromatography
Journal of Chromatography A, 1666, , 2022

25
Vilas-Boas S.M.,da Costa M.C.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Octanol-Water Partition Coefficients and Aqueous Solubility Data of Monoterpenoids: Experimental, Modeling, and Environmental Distribution
Industrial and Engineering Chemistry Research, 61, 3154-3167, 2022

26
Lima L.,Pereira A.I.,Vaz C.,Ferreira O.
Mixture Design: Development of a Graphical User Interface for Determining Mixture Parameters
Iberian Conference on Information Systems and Technologies, CISTI, 2022-June, , 2022

27
Roze F.,Pignat P.,Ferreira O.,Pinho S.P.,Jaubert J.N.,Coniglio L.
Phase equilibria of mixtures involving fatty acid ethyl esters and fat alcohols between 4 and 27 kPa for bioproduct production
Fuel, 306, , 2021

28
Añibarro-Ortega M.,Pinela J.,Ćirić A.,Lopes E.,Molina A.K.,Calhelha R.C.,Soković M.,Ferreira O.,Ferreira I.C.F.R.,Barros L.
Extraction of aloesin from aloe vera rind using alternative green solvents: Process optimization and biological activity assessment
Biology, 10, , 2021

29
Martins M.A.R.,Vilas-Boas S.M.,Cordova I.W.,Carvalho P.J.,Domańska U.,Ferreira O.,Coutinho J.A.P.,Pinho S.P.
Infinite Dilution Activity Coefficients in the Smectic and Isotropic Phases of Tetrafluoroborate-Based Ionic Liquids
Journal of Chemical and Engineering Data, 66, 2587-2596, 2021

30
Vilas-Boas S.M.,Teixeira G.,Rosini S.,Martins M.A.R.,Gaschi P.S.,Coutinho J.A.P.,Ferreira O.,Pinho S.P.
Ionic liquids as entrainers for terpenes fractionation and other relevant separation problems
Journal of Molecular Liquids, 323, , 2021

31
Lima L.A.,Pereira A.I.,Vaz C.B.,Ferreira O.,Carocho M.,Barros L.
Dynamic Response Surface Method Combined with Genetic Algorithm to Optimize Extraction Process Problem
Communications in Computer and Information Science, 1488 CCIS, 3-14, 2021

32
Vilas-Boas S.M.,Alves R.S.,Brandão P.,Campos L.M.A.,Coutinho J.A.P.,Pinho S.P.,Ferreira O.
Solid-liquid phase equilibrium of trans-cinnamic acid, p-coumaric acid and ferulic acid in water and organic solvents: Experimental and modelling studies
Fluid Phase Equilibria, 521, , 2020

33
Pérez-Sánchez G.,Santos Y.S.,Ferreira O.,Coutinho J.A.P.,Gomes J.R.B.,Pinho S.P.
The cation effect on the solubility of glycylglycine and N-acetylglycine in aqueous solution: Experimental and molecular dynamics studies
Journal of Molecular Liquids, 310, , 2020

34
Vieira V.,Calhelha R.C.,Barros L.,Coutinho J.A.P.,Ferreira I.C.F.R.,Ferreira O.
Insights on the extraction performance of alkanediols and glycerol: Using Juglans regia L. Leaves as a source of bioactive compounds
Molecules, 25, , 2020

35
Vieira V.,Pereira C.,Abreu R.M.V.,Calhelha R.C.,Alves M.J.,Coutinho J.A.P.,Ferreira O.,Barros L.,Ferreira I.C.F.R.
Hydroethanolic extract of Juglans regia L. green husks: A source of bioactive phytochemicals
Food and Chemical Toxicology, 137, , 2020

36
Vilas-Boas S.M.,Abranches D.O.,Crespo E.A.,Ferreira O.,Coutinho J.A.P.,Pinho S.P.
Experimental solubility and density studies on aqueous solutions of quaternary ammonium halides, and thermodynamic modelling for melting enthalpy estimations
Journal of Molecular Liquids, 300, , 2020

37
Vilas-Boas S.M.,Pokorný V.,Štejfa V.,Ferreira O.,Pinho S.P.,Růžička K.,Fulem M.
Vapor pressure and thermophysical properties of eugenol and (+)-carvone
Fluid Phase Equilibria, 499, , 2019

38
Vilas-Boas S.M.,Vieira V.,Brandão P.,Alves R.S.,Coutinho J.A.P.,Pinho S.P.,Ferreira O.
Solvent and temperature effects on the solubility of syringic, vanillic or veratric acids: Experimental, modeling and solid phase studies
Journal of Molecular Liquids, 289, , 2019

39
Vieira V.,Pereira C.,Pires T.C.S.P.,Calhelha R.C.,Alves M.J.,Ferreira O.,Barros L.,Ferreira I.C.F.R.
Phenolic profile, antioxidant and antibacterial properties of Juglans regia L. (walnut) leaves from the Northeast of Portugal
Industrial Crops and Products, 134, 347-355, 2019

40
Vilas-Boas S.M.,Brandão P.,Martins M.A.R.,Silva L.P.,Schreiner T.B.,Fernandes L.,Ferreira O.,Pinho S.P.
Solubility and solid phase studies of isomeric phenolic acids in pure solvents
Journal of Molecular Liquids, 272, 1048-1057, 2018

41
Soares B.P.,Štejfa V.,Ferreira O.,Pinho S.P.,Růžička K.,Fulem M.
Vapor pressures and thermophysical properties of selected ethanolamines
Fluid Phase Equilibria, 473, 245-254, 2018

42
Crespo E.A.,Silva L.P.,Martins M.A.R.,Bülow M.,Ferreira O.,Sadowski G.,Held C.,Pinho S.P.,Coutinho J.A.P.
The Role of Polyfunctionality in the Formation of [Ch]Cl-Carboxylic Acid-Based Deep Eutectic Solvents
Industrial and Engineering Chemistry Research, 57, 11195-11209, 2018

43
Vieira V.,Prieto M.A.,Barros L.,Coutinho J.A.P.,Ferreira I.C.F.R.,Ferreira O.
Enhanced extraction of phenolic compounds using choline chloride based deep eutectic solvents from Juglans regia L.
Industrial Crops and Products, 115, 261-271, 2018

44
Vieira V.,Prieto M.A.,Barros L.,Coutinho J.A.P.,Ferreira O.,Ferreira I.C.F.R.
Optimization and comparison of maceration and microwave extraction systems for the production of phenolic compounds from Juglans regia L. for the valorization of walnut leaves
Industrial Crops and Products, 107, 341-352, 2017

45
Crespo E.A.,Silva L.P.,Martins M.A.R.,Fernandez L.,Ortega J.,Ferreira O.,Sadowski G.,Held C.,Pinho S.P.,Coutinho J.A.P.
Characterization and Modeling of the Liquid Phase of Deep Eutectic Solvents Based on Fatty Acids/Alcohols and Choline Chloride
Industrial and Engineering Chemistry Research, 56, 12192-12202, 2017

46
Fernandez L.,Silva L.P.,Martins M.A.R.,Ferreira O.,Ortega J.,Pinho S.P.,Coutinho J.A.P.
Indirect assessment of the fusion properties of choline chloride from solid-liquid equilibria data
Fluid Phase Equilibria, 448, 9-14, 2017

47
Martins M.A.R.,Silva L.P.,Ferreira O.,Schröder B.,Coutinho J.A.P.,Pinho S.P.
Terpenes solubility in water and their environmental distribution
Journal of Molecular Liquids, 241, 996-1002, 2017

48
Casimiro F.M.,Constantino D.S.M.,Pereira C.S.M.,Ferreira O.,Rodrigues A.E.,Pinho S.P.
Vapor-Liquid Equilibrium of Binary Mixtures Containing Isopropyl Acetate and Alkanols at 101.32 kPa
Journal of Chemical and Engineering Data, 60, 3181-3186, 2015

49
50
Tomé L.I.N.,Sousa C.S.R.,Gomes J.R.B.,Ferreira O.,Coutinho J.A.P.,Pinho S.P.
Understanding the cation specific effects on the aqueous solubility of amino acids: From mono to polyvalent cations
RSC Advances, 5, 15024-15034, 2015

51
Mota P.C.,Ferreira O.,Hnědkovský L.,Pinho S.P.,Cibulka I.
Partial molar volumes of l-serine and l-threonine in aqueous ammonium sulfate solutions at (278.15, 288.15, 298.15, and 308.15) k
Journal of Solution Chemistry, 43, 283-297, 2014

52
Martins M.A.R.,Ferreira O.,Hnědkovský L.,Cibulka I.,Pinho S.P.
Partial molar volumes of glycine and dl-alanine in aqueous ammonium sulfate solutions at 278.15, 288.15, 298.15 and 308.15 K
Journal of Solution Chemistry, 43, 972-988, 2014

53
Pereira A.I.,Ferreira O.,Pinho S.P.,Fernandes E.M.G.P.
Multilocal Programming and Applications
Intelligent Systems Reference Library, 38, 157-186, 2013

54
Ferreira O.,Schröder B.,Pinho S.P.
Solubility of hesperetin in mixed solvents
Journal of Chemical and Engineering Data, 58, 2616-2621, 2013

55
Ferreira O.,Pinho S.P.
Solubility of flavonoids in pure solvents
Industrial and Engineering Chemistry Research, 51, 6586-6590, 2012

56
Couto R.,Vidinha P.,Peres C.,Ribeiro A.S.,Ferreira O.,Oliveira M.V.,MacEdo E.A.,Loureiro J.M.,Barreiros S.
Geranyl acetate synthesis in a packed-bed reactor catalyzed by novozym in supercritical carbon dioxide and in supercritical ethane
Industrial and Engineering Chemistry Research, 50, 1938-1946, 2011

57
Rodrigues V.,Pereira A.I.,Ferreira O.,Pinho S.P.
Liquid phase stability via global optimization
AIP Conference Proceedings, 1281, 991-994, 2010

58
Ribeiro A.S.,Oliveira M.V.,Rebocho S.F.,Ferreira O.,Vidinha P.,Barreiros S.,MacEdo E.A.,Loureiro J.M.
Enzymatic production of decyl acetate: Kinetic study in n -hexane and comparison with supercritical CO2
Industrial and Engineering Chemistry Research, 49, 7168-7175, 2010

59
Casás L.M.,Orge B.,Ferreira O.
Liquid-liquid equilibria of mixtures containing methyl acetate + methanol + hexane or heptane
Journal of Chemical and Engineering Data, 53, 89-93, 2008

60
Ferreira O.,MacEdo E.A.,Brignole E.A.
Application of the GCA-EoS model to the supercritical processing of fatty oil derivatives
Journal of Food Engineering, 70, 579-587, 2005

61
Garcia S.,Vidinha P.,Arvana H.,Gomes Da Silva M.D.R.,Ferreira M.O.,Cabral J.M.S.,MacEdo E.A.,Harper N.,Barreiros S.
Cutinase activity in supercritical and organic media: Water activity, solvation and acid-base effects
Journal of Supercritical Fluids, 35, 62-69, 2005

62
Ferreira O.,Macedo E.A.,Bottini S.B.
Extension of the A-UNIFAC model to mixtures of cross- and self-associating compounds
Fluid Phase Equilibria, 227, 165-176, 2005

63
Ferreira O.,Brignole E.A.,Macedo E.A.
Modelling of phase equilibria for associating mixtures using an equation of state
Journal of Chemical Thermodynamics, 36, 1105-1117, 2004

64
Ferreira O.,Brignole E.A.,Macedo E.A.
Phase Equilibria in Sugar Solutions Using the A-UNIFAC Model
Industrial and Engineering Chemistry Research, 42, 6212-6222, 2003

65
Ferreira O.,Fornari T.,Brignole E.,Bottini S.
Modeling of association effects in mixtures of carboxylic acids with associating and non-associating components
Latin American Applied Research, 33, 307-312, 2003

66
Ferreira O.,Foco G.M.
Infinite dilution activity coefficients of solvents in fatty oil derivatives
Latin American Applied Research, 33, 257-260, 2003

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